Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the
brain results in the most severe form of extrapulmonary TB, tuberculous meningitis (TBM) …

Tuberculous meningitis (TBM) results from dissemination of M. tuberculosis to the
cerebrospinal fluid (CSF) and meninges. Ischaemia, hydrocephalus and raised intracranial …

Most antibiotics are produced by soil microbes and typically interfere with macromolecular
synthesis processes as their antibacterial mechanism of action. These natural products are …

Recent studies in the field of CNS-TB have largely focussed on TB meningitis. The outcome
may improve by optimizing treatment dosing. This needs to be confirmed in clinical trials …

Central nervous system (CNS) infections continue to be associated with significant
neurological morbidity and mortality despite various existing therapies. Adjunctive steroid …

Background Tuberculous meningitis is the most devastating presentation of disease with
Mycobacterium tuberculosis. We sought to evaluate treatment outcomes for adult patients …

Background Tuberculous meningitis (TBM) is one of the most life-threatening infectious
diseases. We performed a systematic review and meta-analysis of the clinical features …

Tuberculosis (TB) is the most prevalent infectious disease in the world. In recent years there
has been a significant increase in the incidence of TB due to the emergence of multidrug …

Tuberculous meningitis (TBM) presents a critical neurologic emergency characterized by
high mortality and morbidity rates, necessitating immediate therapeutic intervention, often …

Introduction Meningitis is the most severe manifestation of tuberculosis, resulting in death or
disability in over 50% of those affected, with even higher morbidity and mortality among …