Prostate cancer is the most commonly diagnosed cancer affecting men in the United States.
The prostate is a hormone-dependent gland in which androgen hormones testosterone and …

The major impact produced by the severe acute respiratory syndrome coronavirus 2 (SARS‑
CoV‑2) focused many researchers attention to find treatments that can suppress …

Viruses manipulate cellular metabolism and macromolecule recycling processes like
autophagy. Dysregulated metabolism might lead to excessive inflammatory and …

The introduction of second-generation androgen receptor antagonists (SG-ARAs) has
greatly impacted the treatment of metastatic prostate cancer, providing tolerable and …

Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

Vaccines have reduced the transmission and severity of COVID‐19, but there remains a
paucity of efficacious treatment for drug‐resistant strains and more susceptible individuals …

Overcoming multidrug resistance represents a major challenge for cancer treatment. In the
search for new chemotherapeutics to treat malignant diseases, drug repurposing gained a …

Background Coronavirus disease 19 (COVID-19) is spreading globally and treatment
options remain limited. A formulation of niclosamide, a potent anti-SARS-CoV-2 agent and a …

Ovarian cancer is the leading cause of death from gynecologic malignancy in the Western
world. This is due, in part, to the fact that despite standard treatment of surgery and …

Niclosamide (NIC) has demonstrated promising in vitro antiviral efficacy against SARS-CoV-
2, the causative agent of the COVID-19 pandemic. Though NIC is already FDA-approved …