Our understanding of tumor-infiltrating lymphocytes (TILs) is rapidly expanding beyond T cell-
centric perspectives to include B cells and plasma cells, collectively referred to as TIL-Bs. In …

Whereas T cells have been considered the major immune cells of the tumor
microenvironment able to induce tumor regression and control cancer clinical outcome, a …

Glioblastomas are aggressive brain tumors that are largely immunotherapy resistant. This is
associated with immunosuppression and a dysfunctional tumor vasculature, which hinder T …

Tumors and their surrounding area represent spatially organized “ecosystems”, where tumor
cells and the immune contextures of the different compartments are in a dynamic interplay …

Background Ectopic lymphoid formations are called tertiary lymphoid structures (TLSs).
TLSs in cancer have been reported to be associated with good prognosis and …

Immunotherapy has experienced remarkable growth recently. Tertiary lymphoid structures
(TLSs) and B cells may play a key role in the immune response and have a survival benefit …

Tumor-associated tertiary lymphoid structures (TLSs) are ectopic lymphoid formations within
tumor tissue, with mainly B and T cell populations forming the organic aggregates. The …

Objective To evaluate the presence and subtypes of tertiary lymphatic structures (TLSs) in
urothelial carcinoma of the bladder (UCB) and to analyze their associated …

Tertiary lymphoid structures (TLSs) are formations at sites with persistent inflammatory
stimulation, including tumors. These ectopic lymphoid organs mainly consist of chemo …

Tertiary lymphoid structures (TLSs) are organized aggregates of immune cells in non-
lymphoid tissues and are associated with a favorable prognosis in tumors. However, TLS …