Our lungs are exposed daily to airborne pollutants, particulate matter, pathogens as well as
lung allergens and irritants. Exposure to these substances can lead to inflammatory …

Oxidative stress in the bronchopulmonary airways can occur through a variety of
inflammatory mechanisms and also following the inhalation of environmental pollutants …

Rationale Environmental tobacco smoke (ETS) exposure increases asthma risk in children.
There is limited knowledge of prenatal ETS for adult-onset asthma. Objectives To determine …

Background: Lung injury resulting from oxidative stress contributes to bronchopulmonary
dysplasia (BPD) pathogenesis. Nuclear factor erythroid-2 related factor-2 (NFE2L2) …

Lung inflammation resulting from oxidant/antioxidant imbalance is a common feature of
many lung diseases. In particular, the role of enzymes regulated by the NF-E2-related factor …

In recent years, genome-wide association studies (GWAS) have identified more than 300
validated associations between genetic variants and risk of approximately 70 common …

Background We previously reported that asthmatic children with GSTM1 null genotype may
be more susceptible to the acute effect of ozone on the small airways and might benefit from …

В настоящее время остается актуальным изучение влияния негативных факторов
окружающей среды и пищевых веществ на экспрессию генов. Цель исследования …

Проанализированы и систематизированы данные мировой литературы последних лет
по генетико-биохимическим механизмам вовлечённости ферментов антиоксидантной …

■ Abstract Background: Asthma is a complex multifactorial disease that is not yet fully
understood. Oxidative stress due to an imbalance between the oxidative forces and the …