Kaposi sarcoma

E Cesarman, B Damania, SE Krown, J Martin… - Nature reviews Disease …, 2019 - nature.com
Kaposi sarcoma (KS) gained public attention as an AIDS-defining malignancy; its
appearance on the skin was a highly stigmatizing sign of HIV infection during the height of …

Human viral oncogenesis: a cancer hallmarks analysis

EA Mesri, MA Feitelson, K Munger - Cell host & microbe, 2014 - cell.com
Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Kaposi's sarcoma and its associated herpesvirus

EA Mesri, E Cesarman, C Boshoff - Nature Reviews Cancer, 2010 - nature.com
Kaposi's sarcoma (KS) is the most common cancer in HIV-infected untreated individuals.
Kaposi's sarcoma-associated herpesvirus (KSHV; also known as human herpesvirus 8 …

Construction and manipulation of a new Kaposi's sarcoma-associated herpesvirus bacterial artificial chromosome clone

KF Brulois, H Chang, ASY Lee, A Ensser… - Journal of …, 2012 - Am Soc Microbiol
Efficient genetic modification of herpesviruses such as Kaposi's sarcoma-associated
herpesvirus (KSHV) has come to rely on bacterial artificial chromosome (BAC) technology …

KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine

D Ganem - The Journal of clinical investigation, 2010 - Am Soc Clin Investig
The linkage of Kaposi sarcoma (KS) to infection by a novel human herpesvirus (Kaposi
sarcoma–associated herpesvirus [KSHV]) is one of the great successes of contemporary …

Kaposi sarcoma–associated herpesvirus: immunobiology, oncogenesis, and therapy

DP Dittmer, B Damania - The Journal of clinical …, 2016 - Am Soc Clin Investig
Kaposi sarcoma–associated herpesvirus (KSHV), also known as human herpesvirus 8, is
the etiologic agent underlying Kaposi sarcoma, primary effusion lymphoma, and multicentric …

Regulation of KSHV latency and lytic reactivation

G Broussard, B Damania - Viruses, 2020 - mdpi.com
Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with three malignancies—
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's …

Cohesins localize with CTCF at the KSHV latency control region and at cellular c‐myc and H19/Igf2 insulators

W Stedman, H Kang, S Lin, JL Kissil… - The EMBO …, 2008 - embopress.org
Cohesins, which mediate sister chromatin cohesion, and CTCF, which functions at
chromatin boundaries, play key roles in the structural and functional organization of …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Kaposi sarcoma herpesvirus pathogenesis

G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …