[HTML][HTML] Recent advances and perspectives of nucleic acid detection for coronavirus
M Shen, Y Zhou, J Ye, AAA Al-Maskri, Y Kang… - Journal of …, 2020 - Elsevier
The recent pneumonia outbreak caused by a novel coronavirus (SARS-CoV-2) is posing a
great threat to global public health. Therefore, rapid and accurate identification of …
great threat to global public health. Therefore, rapid and accurate identification of …
Application of the CRISPR/Cas9-based gene editing technique in basic research, diagnosis, and therapy of cancer
H Zhang, C Qin, C An, X Zheng, S Wen, W Chen, X Liu… - Molecular cancer, 2021 - Springer
Abstract The 2020 Nobel Prize in Chemistry was awarded to Emmanuelle Charpentier and
Jennifer Doudna for the development of the Clustered regularly interspaced short …
Jennifer Doudna for the development of the Clustered regularly interspaced short …
Programmable RNA editing with compact CRISPR–Cas13 systems from uncultivated microbes
Competitive coevolution between microbes and viruses has led to the diversification of
CRISPR–Cas defense systems against infectious agents. By analyzing metagenomic …
CRISPR–Cas defense systems against infectious agents. By analyzing metagenomic …
[HTML][HTML] Development of CRISPR as an antiviral strategy to combat SARS-CoV-2 and influenza
Summary The coronavirus disease 2019 (COVID-19) pandemic, caused by the SARS-CoV-
2 virus, has highlighted the need for antiviral approaches that can target emerging viruses …
2 virus, has highlighted the need for antiviral approaches that can target emerging viruses …
Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA
D Wang, S He, X Wang, Y Yan, J Liu, S Wu… - Nature Biomedical …, 2020 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for
rapid and accurate nucleic acid detection at the point of care. Here, we report an …
rapid and accurate nucleic acid detection at the point of care. Here, we report an …
Electrochemical SARS-CoV-2 sensing at point-of-care and artificial intelligence for intelligent COVID-19 management
To manage the COVID-19 pandemic, development of rapid, selective, sensitive diagnostic
systems for early stage β-coronavirus severe acute respiratory syndrome (SARS-CoV-2) …
systems for early stage β-coronavirus severe acute respiratory syndrome (SARS-CoV-2) …
Massively parallel Cas13 screens reveal principles for guide RNA design
Type VI CRISPR enzymes are RNA-targeting proteins with nuclease activity that enable
specific and robust target gene knockdown without altering the genome. To define rules for …
specific and robust target gene knockdown without altering the genome. To define rules for …
Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents
Cas13a has been used to target RNA viruses in cell culture, but efficacy has not been
demonstrated in animal models. In this study, we used messenger RNA (mRNA)-encoded …
demonstrated in animal models. In this study, we used messenger RNA (mRNA)-encoded …
Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment
Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
infectious inflammatory diseases, which continuously pose one of the most serious threats to …
CRISPR technologies for genome, epigenome and transcriptome editing
Our ability to edit genomes lags behind our capacity to sequence them, but the growing
understanding of CRISPR biology and its application to genome, epigenome and …
understanding of CRISPR biology and its application to genome, epigenome and …