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Microenvironment‐based diabetic foot ulcer nanomedicine
F Huang, X Lu, Y Yang, Y Yang, Y Li, L Kuai… - Advanced …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFU), one of the most serious complications of diabetes, are essentially
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …
chronic, nonhealing wounds caused by diabetic neuropathy, vascular disease, and bacterial …
Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration
DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …
[HTML][HTML] Oral wound healing models and emerging regenerative therapies
Following injury, the oral mucosa undergoes complex sequences of biological healing
processes to restore homeostasis. While general similarities exist, there are marked …
processes to restore homeostasis. While general similarities exist, there are marked …
[PDF][PDF] A combination therapy using electrical stimulation and adaptive, conductive hydrogels loaded with self‐assembled nanogels incorporating short interfering RNA …
H Lei, D Fan - Advanced Science, 2022 - Wiley Online Library
In addition to oxidative stress and impaired angiogenesis, the overexpression of
metalloproteinases (MMPs) and proinflammatory cytokines, which are promoted by …
metalloproteinases (MMPs) and proinflammatory cytokines, which are promoted by …
Neuropathy and diabetic foot syndrome
M Volmer-Thole, R Lobmann - International journal of molecular sciences, 2016 - mdpi.com
Diabetic foot ulceration is a serious complication of diabetes mellitus worldwide and the
most common cause of hospitalization in diabetic patients. The etiology of diabetic foot …
most common cause of hospitalization in diabetic patients. The etiology of diabetic foot …
Pathogenesis and treatment of impaired wound healing in diabetes mellitus: new insights
Diabetic foot ulcers (DFUs) are one of the most common and serious complications of
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …
diabetes mellitus, as wound healing is impaired in the diabetic foot. Wound healing is a …
The role of bacterial biofilms in chronic infections
T Bjarnsholt - Apmis, 2013 - Wiley Online Library
Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …
100 years. These infections killed millions of people in previous centuries, but they have …
Current therapeutic strategies in diabetic foot ulcers
Diabetic foot ulcers (DFUs) are the fastest growing chronic complication of diabetes mellitus,
with more than 400 million people diagnosed globally, and the condition is responsible for …
with more than 400 million people diagnosed globally, and the condition is responsible for …
Stimuli-responsive therapeutic systems for the treatment of diabetic infected wounds
Diabetic wound infection is a common disease that has significantly reduced people's
quality of life. Although tremendous achievements have been made in clinical treatment, the …
quality of life. Although tremendous achievements have been made in clinical treatment, the …
Proteases and delayed wound healing
SM McCarty, SL Percival - Advances in wound care, 2013 - liebertpub.com
Significance: Proteases and their inhibitors contribute to the balance between extracellular
matrix (ECM) degradation and deposition, creating an equilibrium that is essential for the …
matrix (ECM) degradation and deposition, creating an equilibrium that is essential for the …