[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

Nanostructured lipid carriers (NLC) system: A novel drug targeting carrier

VR Salvi, P Pawar - Journal of Drug Delivery Science and Technology, 2019 - Elsevier
Lipid nanocarriers are developed as an alternative to polymeric nanoparticles, liposomes
and emulsions. Further, Nanostructured Lipid Nanocarriers are the second generation lipid …

Stimuli-responsive In situ gelling system for nose-to-brain drug delivery

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
The diagnosis and treatment of neurological ailments always remain an utmost challenge for
research fraternity due to the presence of BBB. The intranasal route appeared as an …

Key for crossing the BBB with nanoparticles: The rational design

SM Lombardo, M Schneider, AE Türeli… - Beilstein journal of …, 2020 - beilstein-journals.org
Central nervous system diseases are a heavy burden on society and health care systems.
Hence, the delivery of drugs to the brain has gained more and more interest. The brain is …

[HTML][HTML] Design and optimization of curcumin loaded nano lipid carrier system using Box-Behnken design

M Agrawal, S Saraf, M Pradhan, RJ Patel… - Biomedicine & …, 2021 - Elsevier
Herbal antioxidant like curcumin holds great potential to treat neurodegenerative disease
like Alzheimer's disease. However, its therapeutic potency is obstructed due to rapid …

Surface-modified nanocarriers for nose-to-brain delivery: from bioadhesion to targeting

F Sonvico, A Clementino, F Buttini, G Colombo… - Pharmaceutics, 2018 - mdpi.com
In the field of nasal drug delivery, nose-to-brain delivery is among the most fascinating
applications, directly targeting the central nervous system, bypassing the blood brain barrier …

Curcumin loaded nanostructured lipid carriers for enhanced skin retained topical delivery: optimization, scale-up, in-vitro characterization and assessment of ex-vivo …

VK Rapalli, V Kaul, T Waghule, S Gorantla… - European Journal of …, 2020 - Elsevier
Nanostructured lipid carriers (NLC) have become a promising drug delivery system for
topical delivery of drugs. Delivery of lipophilic drugs with improved stability and entrapment …

Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting

M Agrawal, S Saraf, S Saraf, SK Dubey, A Puri… - Journal of Controlled …, 2020 - Elsevier
In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

[HTML][HTML] Development of atomoxetine-loaded NLC in situ gel for nose-to-brain delivery: Optimization, in vitro, and preclinical evaluation

D Mohanty, OA Alsaidan, A Zafar, T Dodle, JK Gupta… - Pharmaceutics, 2023 - mdpi.com
The present study investigates the brain-targeted efficiency of atomoxetine (AXT)-loaded
nanostructured lipid carrier (NLC)-laden thermosensitive in situ gel after intranasal …

Smart materials: in situ gel-forming systems for nasal delivery

C Karavasili, DG Fatouros - Drug discovery today, 2016 - Elsevier
In the last decade in situ gelling systems have emerged as a novel approach in intranasal
delivery of therapeutics, capturing the interest of scientific community. Considerable …