The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

Pyran is an oxygen-containing heterocyclic moiety, which exhibits an array of
pharmacological properties. Pyran is also one of the important structural subunits found …

Abstract β-Lapachone (β-lap, 1), an ortho-naphthoquinone natural product isolated from the
lapacho tree (Tabebuia avellanedae) in many regions of South America, has received …

This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-
lapachone, a naphthoquinone, as well as their derivatives, in the development of new drug …

Naphthoquinones are of key importance in organic synthesis and medicinal chemistry. In the
last few years, various synthetic routes have been developed to prepare bioactive …

Naphthoquinoidal compounds are of great interest in medicinal chemistry. In recent years,
several synthetic routes have been developed to obtain bioactive molecules derived from …

Nature has been a rich source of therapeutic agents for thousands of years and an
impressive number of modern drugs have been isolated from natural sources based on the …

Naphthoquinones have been found to have a wide range of biological activities, including
cytotoxicity to cancer cells. The secondary metabolites lapachol, α-and β-lapachone and a …

Oral squamous cell carcinoma (OSCC) is a worldwide public health problem, accounting for
approximately 90% of all oral cancers, and is the eighth most common cancer in men …

This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone,
examples of bioactive natural products that still being under biological evaluation and …