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Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
J Guo, X Huang, L Dou, M Yan, T Shen… - Signal transduction and …, 2022 - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …
tissue and cell functions and significant increases in the risks of various aging-related …
Mental health care for older adults: recent advances and new directions in clinical practice and research
CF Reynolds 3rd, DV Jeste, PS Sachdev… - World …, 2022 - Wiley Online Library
The world's population is aging, bringing about an ever‐greater burden of mental disorders
in older adults. Given multimorbidities, the mental health care of these people and their …
in older adults. Given multimorbidities, the mental health care of these people and their …
Challenges and hopes for Alzheimer's disease
SA Tatulian - Drug discovery today, 2022 - Elsevier
Recent drug development efforts targeting Alzheimer's disease (AD) have failed to produce
effective disease-modifying agents for many reasons, including the substantial …
effective disease-modifying agents for many reasons, including the substantial …
Applications of machine learning to diagnosis and treatment of neurodegenerative diseases
Globally, there is a huge unmet need for effective treatments for neurodegenerative
diseases. The complexity of the molecular mechanisms underlying neuronal degeneration …
diseases. The complexity of the molecular mechanisms underlying neuronal degeneration …
Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease
M Kivipelto, F Mangialasche, T Ngandu - Nature Reviews Neurology, 2018 - nature.com
Research into dementia prevention is of paramount importance if the dementia epidemic is
to be halted. Observational studies have identified several potentially modifiable risk factors …
to be halted. Observational studies have identified several potentially modifiable risk factors …
World‐Wide FINGERS Network: a global approach to risk reduction and prevention of dementia
M Kivipelto, F Mangialasche, HM Snyder… - Alzheimer's & …, 2020 - Wiley Online Library
Reducing the risk of dementia can halt the worldwide increase of affected people. The
multifactorial and heterogeneous nature of late‐onset dementia, including Alzheimer's …
multifactorial and heterogeneous nature of late‐onset dementia, including Alzheimer's …
Dementia prevention, intervention, and care
Acting now on dementia prevention, intervention, and care will vastly improve living and
dying for individuals with dementia and their families, and in doing so, will transform the …
dying for individuals with dementia and their families, and in doing so, will transform the …
Alzheimer's disease prevention: from risk factors to early intervention
M Crous-Bou, C Minguillón, N Gramunt… - Alzheimer's research & …, 2017 - Springer
Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a
healthcare burden of epidemic proportions for which there is currently no cure …
healthcare burden of epidemic proportions for which there is currently no cure …
Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review
RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …
typically characterized by memory loss, personality changes, and a decline in overall …
Defeating Alzheimer's disease and other dementias: a priority for European science and society
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …