Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

A growing body of evidence points to the role of glucose variability (GV) in the development
of the microvascular and macrovascular complications of diabetes. In this review, we …

OBJECTIVE Continuous glucose monitoring (CGM) has provided new measures of glycemic
control that link to diabetes complications. This study investigated the association between …

The aim of this article is to describe the current and potential clinical translation of
pharmacological inhibitors of poly (ADP-ribose) polymerase (PARP) for the therapy of …

Ischemia/reperfusion, which is characterized by deficient oxygen supply and subsequent
restoration of blood flow, can cause irreversible damages to tissue. Mechanisms contributing …

Overall lowering of glucose is of pivotal importance in the treatment of diabetes, with proven
beneficial effects on microvascular and macrovascular outcomes. Still, patients with similar …

The goal of the present studies was to investigate the role of changes in hydrogen sulfide
(H2S) homeostasis in the pathogenesis of hyperglycemic endothelial dysfunction. Exposure …

Diabetes is associated with a two to three-fold increase in risk of cardiovascular disease.
However, intensive glucose-lowering therapy aiming at reducing HbA1c to a near-normal …

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus that
affects approximately half of patients with diabetes. Current treatment regimens cannot treat …

Objective. The objective of this study is to investigate the relationship between time in range
(TIR), a new metric of continuous glucose monitoring (CGM) and cardiovascular autonomic …