[HTML][HTML] A Genome-Scale Metabolic Model of 2,3-Butanediol Production by Thermophilic Bacteria Geobacillus icigianus

M Kulyashov, SE Peltek, IR Akberdin - Microorganisms, 2020 - mdpi.com
The thermophilic strain of the genus Geobacillus, Geobacillus icigianus is a promising
bacterial chassis for a wide range of biotechnological applications. In this study, we explored …

Analyzing and designing cell factories with OptFlux

P Vilaça, P Maia, H Giesteira, I Rocha… - … and Modeling: Methods …, 2018 - Springer
OptFlux was launched in 2010 as the first open-source and user-friendly platform containing
all the major methods for performing metabolic engineering tasks in silico. Main features …

Identification of robust strain designs via tandem pfba/lmoma phenotype prediction

P Maia, I Rocha, M Rocha - Proceedings of the Genetic and Evolutionary …, 2017 - dl.acm.org
The past two decades have witnessed great advances in the computational modeling and
systems biology fields. Soon after the first models of metabolism were developed, methods …

Integrating kinetic and constraint-based models of metabolism

MM Pereira - 2022 - repositorium.uminho.pt
Mathematical models are fundamental tools for explaining biological behaviors. Dynamical
and constraint-based models are two different formulations that attempt to capture the …

Integrating knowledge from data and literature for building transcriptional regulatory networks

RT Pereira - 2016 - search.proquest.com
Abstract Research in the Systems Biology field has been steadily increasing and one of the
most addressed topics is the modelling and simulation of biological systems, whose aim is to …