Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical applications
Although sex and gender are recognized as major determinants of health and immunity,
their role is rarely considered in clinical practice and public health. We identified six …
their role is rarely considered in clinical practice and public health. We identified six …
The legacy of larval infection on immunological dynamics over metamorphosis
Insect metamorphosis promotes the exploration of different ecological niches, as well as
exposure to different parasites, across life stages. Adaptation should favour immune …
exposure to different parasites, across life stages. Adaptation should favour immune …
Schedule and magnitude of reproductive investment under immune trade-offs explains sex differences in immunity
Sex differences in immunity are found in many species. Known immune mechanisms in
birds and mammals suggest that pathogen detection may be amplified in females, whereas …
birds and mammals suggest that pathogen detection may be amplified in females, whereas …
Protective microbiomes can limit the evolution of host pathogen defense
The evolution of host immunity occurs in the context of the microbiome, but little theory exists
to predict how resistance against pathogens might be influenced by the need to tolerate and …
to predict how resistance against pathogens might be influenced by the need to tolerate and …