Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

[HTML][HTML] Antibiotics as major disruptors of gut microbiota

J Ramirez, F Guarner, L Bustos Fernandez… - Frontiers in cellular …, 2020 - frontiersin.org
Advances in culture-independent research techniques have led to an increased
understanding of the gut microbiota and the role it plays in health and disease. The intestine …

Autism-related dietary preferences mediate autism-gut microbiome associations

CX Yap, AK Henders, GA Alvares, DLA Wood… - Cell, 2021 - cell.com
There is increasing interest in the potential contribution of the gut microbiome to autism
spectrum disorder (ASD). However, previous studies have been underpowered and have …

Effects of early-life antibiotics on the develo** infant gut microbiome and resistome: a randomized trial

M Reyman, MA Van Houten, RL Watson… - Nature …, 2022 - nature.com
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have
pronounced effects on gut microbiome development and selection of antimicrobial …

Engineering living therapeutics with synthetic biology

A Cubillos-Ruiz, T Guo, A Sokolovska… - Nature Reviews Drug …, 2021 - nature.com
The steadfast advance of the synthetic biology field has enabled scientists to use genetically
engineered cells, instead of small molecules or biologics, as the basis for the development …

Inflammatory bowel diseases (IBD) and the microbiome—searching the crime scene for clues

M Lee, EB Chang - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial,
immunological, and genetic factors. Alterations in the gut microbiota have been associated …

RESCRIPt: Reproducible sequence taxonomy reference database management

MS Robeson, DR O'Rourke, BD Kaehler… - PLoS computational …, 2021 - journals.plos.org
Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …

[HTML][HTML] Developmental trajectory of the healthy human gut microbiota during the first 5 years of life

J Roswall, LM Olsson, P Kovatcheva-Datchary… - Cell host & …, 2021 - cell.com
The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …

[HTML][HTML] Mother-to-infant microbiota transmission and infant microbiota development across multiple body sites

D Bogaert, GJ Van Beveren, EM de Koff, PL Parga… - Cell Host & Microbe, 2023 - cell.com
Early-life microbiota seeding and subsequent development is crucial to future health.
Cesarean-section (CS) birth, as opposed to vaginal delivery, affects early mother-to-infant …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …