The role of immune cells and mediators in preeclampsia
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …
IL-17 family: cytokines, receptors and signaling
C Gu, L Wu, X Li - Cytokine, 2013 - Elsevier
Abstract The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A–F, plays
crucial roles in host defense against microbial organisms and in the development of …
crucial roles in host defense against microbial organisms and in the development of …
CC chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
A Reboldi, C Coisne, D Baumjohann, F Benvenuto… - Nature …, 2009 - nature.com
Interleukin 17–producing T helper cells (T H-17 cells) are important in experimental
autoimmune encephalomyelitis, but their route of entry into the central nervous system …
autoimmune encephalomyelitis, but their route of entry into the central nervous system …
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
The commensal fungus Candida albicans causes oropharyngeal candidiasis (OPC; thrush)
in settings of immunodeficiency. Although disseminated, vaginal, and oral candidiasis are all …
in settings of immunodeficiency. Although disseminated, vaginal, and oral candidiasis are all …
Neutrophils: Cinderella of innate immune system
Neutrophils are the first line of innate immune defense against infectious diseases.
However, since their discovery by Elie Metchnikoff, they have always been considered …
However, since their discovery by Elie Metchnikoff, they have always been considered …
A role for Th1-like Th17 cells in the pathogenesis of inflammatory and autoimmune disorders
Abstract The T helper 17 (Th17) cells contain a dynamic subset of CD4+ T-cells that are able
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …
to develop into other different lineage subsets, including the Th1-like Th17 cells. These cells …
Foxp3+ Regulatory T Cells, Th17 Effector Cells, and Cytokine Environment in Inflammatory Bowel Disease
N Eastaff-Leung, N Mabarrack, A Barbour… - Journal of clinical …, 2010 - Springer
Background Inflammatory bowel disease (IBD) is thought to result from an aberrant immune
response. Inflammation in IBD may be caused by the loss of homeostasis between CD4+ …
response. Inflammation in IBD may be caused by the loss of homeostasis between CD4+ …
Emerging cell and cytokine targets in rheumatoid arthritis
Despite major progress in the treatment of rheumatoid arthritis (RA), strong unmet medical
need remains, as only a minor proportion of patients reach sustained clinical remission. New …
need remains, as only a minor proportion of patients reach sustained clinical remission. New …
Protumor vs antitumor functions of IL-17
G Murugaiyan, B Saha - The Journal of Immunology, 2009 - journals.aai.org
Inflammation appears to be a necessity for both metastasis and elimination of tumor cells. IL-
17, a proinflammatory cytokine produced by Th17 cells, contributes to both the processes by …
17, a proinflammatory cytokine produced by Th17 cells, contributes to both the processes by …
Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension
H Nguyen, VL Chiasson, P Chatterjee… - Cardiovascular …, 2013 - academic.oup.com
Aims Elevated levels of pro-inflammatory cytokine interleukin-17A (IL-17) are associated
with hypertensive autoimmune diseases; however, the connection between IL-17 and …
with hypertensive autoimmune diseases; however, the connection between IL-17 and …