Thirty years of resistance: Zig-zag through the plant immune system

BPM Ngou, P Ding, JDG Jones - The Plant Cell, 2022 - academic.oup.com
Understanding the plant immune system is crucial for using genetics to protect crops from
diseases. Plants resist pathogens via a two-tiered innate immune detection-and-response …

Plant immune networks

BPM Ngou, JDG Jones, P Ding - Trends in plant science, 2022 - cell.com
Plants have both cell-surface and intracellular receptors to recognize diverse self-and non-
self molecules. Cell-surface pattern recognition receptors (PRRs) recognize extracellular …

Mutual potentiation of plant immunity by cell-surface and intracellular receptors

BPM Ngou, HK Ahn, P Ding, JDG Jones - Nature, 2021 - nature.com
The plant immune system involves cell-surface receptors that detect intercellular pathogen-
derived molecules, and intracellular receptors that activate immunity upon detection of …

A comparative overview of the intracellular guardians of plants and animals: NLRs in innate immunity and beyond

Z Duxbury, C Wu, P Ding - Annual review of plant biology, 2021 - annualreviews.org
Nucleotide-binding domain leucine-rich repeat receptors (NLRs) play important roles in the
innate immune systems of both plants and animals. Recent breakthroughs in NLR …

Molecular innovations in plant TIR-based immunity signaling

D Lapin, O Johanndrees, Z Wu, X Li, JE Parker - The Plant Cell, 2022 - academic.oup.com
A protein domain (Toll and Interleukin-1 receptor [TIR]-like) with homology to animal TIRs
mediates immune signaling in prokaryotes and eukaryotes. Here, we present an overview of …

[HTML][HTML] Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network

L Derevnina, MP Contreras, H Adachi, J Upson… - PLoS …, 2021 - journals.plos.org
In plants, nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins can
form receptor networks to confer hypersensitive cell death and innate immunity. One class of …

The mobile SAR signal N-hydroxypipecolic acid induces NPR1-dependent transcriptional reprogramming and immune priming

I Yildiz, M Mantz, M Hartmann, T Zeier, J Kessel… - Plant …, 2021 - academic.oup.com
N-hydroxypipecolic acid (NHP) accumulates in the plant foliage in response to a localized
microbial attack and induces systemic acquired resistance (SAR) in distant leaf tissue …

Time-resolved single-cell and spatial gene regulatory atlas of plants under pathogen attack

T Nobori, A Monell, TA Lee, J Zhou, J Nery, JR Ecker - BioRxiv, 2023 - biorxiv.org
Plant leaf intercellular space provides a nutrient-rich and heterogeneous niche for microbes
that critically impacts plant health. However, how individual plant cells respond to …

[HTML][HTML] The battle within: how pathogen effectors suppress NLR-mediated immunity

C Wu, L Derevnina - Current Opinion in Plant Biology, 2023 - Elsevier
To successfully colonise plants, pathogens must circumvent the plant immune system.
Intracellular immune receptors of the nucleotide-binding leucine-rich repeat (NLR) class of …

A rare PRIMER cell state in plant immunity

T Nobori, A Monell, TA Lee, Y Sakata, S Shirahama… - Nature, 2025 - nature.com
Plants lack specialized and mobile immune cells. Consequently, any cell type that
encounters pathogens must mount immune responses and communicate with surrounding …