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Astrocyte function from information processing to cognition and cognitive impairment
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
The “neuro-glial-vascular” unit: the role of glia in neurovascular unit formation and dysfunction
The neurovascular unit (NVU) is a complex multi-cellular structure consisting of endothelial
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
cells (ECs), neurons, glia, smooth muscle cells (SMCs), and pericytes. Each component is …
Activation of microglia and astrocytes: a roadway to neuroinflammation and Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disease that is of high importance to the
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …
neuroscience world, yet the complex pathogenicity is not fully understood. Inflammation is …
Glial responses to implanted electrodes in the brain
The use of implants that can electrically stimulate or record electrophysiological or
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …
neurochemical activity in nervous tissue is rapidly expanding. Despite remarkable results in …
Astrocytes, neurons, synapses: a tripartite view on cortical circuit development
In the mammalian cerebral cortex neurons are arranged in specific layers and form
connections both within the cortex and with other brain regions, thus forming a complex …
connections both within the cortex and with other brain regions, thus forming a complex …
Questions and (some) answers on reactive astrocytes
C Escartin, O Guillemaud, MA Carrillo‐de Sauvage - Glia, 2019 - Wiley Online Library
Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …
react to virtually all types of pathological alterations in brain homeostasis by significant …
Human astrocytes: structure and functions in the healthy brain
Data collected on astrocytes' physiology in the rodent have placed them as key regulators of
synaptic, neuronal, network, and cognitive functions. While these findings proved highly …
synaptic, neuronal, network, and cognitive functions. While these findings proved highly …
[HTML][HTML] Lactate and BDNF: key mediators of exercise induced neuroplasticity?
Accumulating evidence from animal and human studies supports the notion that physical
exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative …
exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative …
Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning
L Hösli, N Binini, KD Ferrari, L Thieren, ZJ Looser… - Cell reports, 2022 - cell.com
The mechanisms by which astrocytes modulate neural homeostasis, synaptic plasticity, and
memory are still poorly explored. Astrocytes form large intercellular networks by gap junction …
memory are still poorly explored. Astrocytes form large intercellular networks by gap junction …
[HTML][HTML] Lactate as a metabolite and a regulator in the central nervous system
More than two hundred years after its discovery, lactate still remains an intriguing molecule.
Considered for a long time as a waste product of metabolism and the culprit behind …
Considered for a long time as a waste product of metabolism and the culprit behind …