Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy

PR Williamson, JN Jarvis, AA Panackal… - Nature Reviews …, 2017 - nature.com
HIV-associated cryptococcal meningitis is by far the most common cause of adult meningitis
in many areas of the world that have high HIV seroprevalence. In most areas in Sub …

Syndromic panel-based testing in clinical microbiology

P Ramanan, AL Bryson, MJ Binnicker… - Clinical microbiology …, 2018 - Am Soc Microbiol
The recent development of commercial panel-based molecular diagnostics for the rapid
detection of pathogens in positive blood culture bottles, respiratory specimens, stool, and …

Single-dose liposomal amphotericin B treatment for cryptococcal meningitis

JN Jarvis, DS Lawrence, DB Meya… - … England Journal of …, 2022 - Mass Medical Soc
Background Cryptococcal meningitis is a leading cause of human immunodeficiency virus
(HIV)–related death in sub-Saharan Africa. Whether a treatment regimen that includes a …

Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis

R Rajasingham, RM Smith, BJ Park… - The Lancet infectious …, 2017 - thelancet.com
Background Cryptococcus is the most common cause of meningitis in adults living with HIV
in sub-Saharan Africa. Global burden estimates are crucial to guide prevention strategies …

Antifungal combinations for treatment of cryptococcal meningitis in Africa

SF Molloy, C Kanyama, RS Heyderman… - … England Journal of …, 2018 - Mass Medical Soc
Background Cryptococcal meningitis accounts for more than 100,000 human
immunodeficiency virus (HIV)–related deaths per year. We tested two treatment strategies …

Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study

NC Bahr, E Nuwagira, EE Evans… - The Lancet infectious …, 2018 - thelancet.com
Summary Background WHO recommends Xpert MTB/RIF as initial diagnostic testing for
tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about …

[PDF][PDF] Guidelines for the diagnosis, prevention, and management of cryptococcal disease in HIV-infected adults, adolescents and children, March 2018: supplement to …

World Health Organization - 2018 - apps.who.int
GUIDELINES Page 1 GUIDELINES FOR THE DIAGNOSIS, PREVENTION AND
MANAGEMENT OF CRYPTOCOCCAL DISEASE IN HIV-INFECTED ADULTS …

Global morbidity and mortality of central nervous system tuberculosis: a systematic review and meta-analysis

A Navarro-Flores, JE Fernandez-Chinguel… - Journal of …, 2022 - Springer
Background Tuberculosis (TB) is the second most common cause of death due to a single
infectious agent worldwide after COVID-19. Up to 15% of the cases are extrapulmonary, and …

Timing of antiretroviral therapy after diagnosis of cryptococcal meningitis

DR Boulware, DB Meya, C Muzoora… - … England Journal of …, 2014 - Mass Medical Soc
Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency
syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; …

Tuberculous meningitis: more questions, still too few answers

GE Thwaites, R van Toorn, J Schoeman - The Lancet Neurology, 2013 - thelancet.com
Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …