Proteins perform a huge number of central functions in living organisms, thus all the new
techniques allowing their precise, fast and accurate characterization at single-molecule level …

The electrical current blockade of a peptide or protein threading through a nanopore can be
used as a fingerprint of the molecule in biosensor applications. However, threading of full …

We report experimentally the transport of an unfolded protein through a narrow solid-state
nanopore of 3 nm diameter as a function of applied voltage. The random coil polypeptide …

The translocation of macromolecules through a nanopore requires the im**ement of the
molecules at the pore followed by threading through the pore. While most of the discussion …

Understanding protein folding remains a challenge. A difficulty is to investigate
experimentally all the conformations in the energy landscape. Only single molecule …

Single molecule protein sequencing would represent a disruptive burst in proteomic
research with important biomedical impacts. Due to their success in DNA sequencing …

Protein and solid-state nanometer-scale pores are being developed for the detection,
analysis and manipulation of single molecules. In the simplest embodiment, the entry of a …

In this short paper, a correction is made to the recently proposed solution of Li and Talaga to
a 1D biased diffusion model for linear DNA translocation, and a new analysis will be given to …

As biological macromolecules, proteins are involved in important cellular functions ranging
from DNA replication and biosynthesis to metabolic signalling and environmental sensing …

Proteins need to be unfolded when translocated through the pores in mitochondrial and
other cellular membranes. Knotted proteins, however, might get stuck during this process …