From single-to multi-omics: future research trends in medicinal plants

L Yang, Y Yang, L Huang, X Cui… - Briefings in bioinformatics, 2023 - academic.oup.com
Medicinal plants are the main source of natural metabolites with specialised
pharmacological activities and have been widely examined by plant researchers. Numerous …

Connecting omics signatures and revealing biological mechanisms with iLINCS

M Pilarczyk, M Fazel-Najafabadi, M Kouril… - Nature …, 2022 - nature.com
There are only a few platforms that integrate multiple omics data types, bioinformatics tools,
and interfaces for integrative analyses and visualization that do not require programming …

Transcriptional regulation of cancer immune checkpoints: emerging strategies for immunotherapy

S Venkatraman, J Meller, S Hongeng, R Tohtong… - Vaccines, 2020 - mdpi.com
The study of immune evasion has gained a well-deserved eminence in cancer research by
successfully develo** a new class of therapeutics, immune checkpoint inhibitors, such as …

qPTM: an updated database for PTM dynamics in human, mouse, rat and yeast

K Yu, Y Wang, Y Zheng, Z Liu, Q Zhang… - Nucleic Acids …, 2023 - academic.oup.com
Post-translational modifications (PTMs) are critical molecular mechanisms that regulate
protein functions temporally and spatially in various organisms. Since most PTMs are …

S‐adenosylmethionine inhibits la ribonucleoprotein domain family member 1 in murine liver and human liver cancer cells

K Ramani, AE Robinson, J Berlind, W Fan… - …, 2022 - Wiley Online Library
Abstract Background and Aims Methionine adenosyltransferase 1A (MAT1A) is responsible
for S‐adenosylmethionine (SAMe) biosynthesis in the liver. Mice lacking Mat1a have hepatic …

Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS

M Pilarczyk, M Kouril, B Shamsaei, J Vasiliauskas… - BioRxiv, 2019 - biorxiv.org
There are only a few platforms that integrate multiple omics data types, bioinformatics tools,
and interfaces for integrative analyses and visualization that do not require programming …

Argonaut: A web platform for collaborative multi-omic data visualization and exploration

DR Brademan, IJ Miller, NW Kwiecien, DJ Pagliarini… - Patterns, 2020 - cell.com
Researchers now generate large multi-omic datasets using increasingly mature mass
spectrometry techniques at an astounding pace, facing new challenges of" Big Data" …

Mice lacking acid-sensing ion channel 2 in the medial prefrontal cortex exhibit social dominance

B Lin, Z **, G Park, Q Ge, K Singh, WG Ryan V… - Science …, 2024 - science.org
Social dominance is essential for maintaining a stable society and has both positive and
negative impacts on social animals, including humans. However, the regulatory …

ExpressVis: a biologist-oriented interactive web server for exploring multi-omics data

X Liu, K Xu, X Tao, R Yin, G Ren, M Yu, C Li… - Nucleic acids …, 2022 - academic.oup.com
In the era of life-omics, huge amounts of multi-omics data have been generated and widely
used in biomedical research. It is challenging for biologists with limited programming skills to …

dbPTM 2025 update: comprehensive integration of PTMs and proteomic data for advanced insights into cancer research

CR Chung, Y Tang, YP Chiu, S Li… - Nucleic Acids …, 2025 - academic.oup.com
Post-translational modifications (PTMs) are essential for modulating protein function and
influencing stability, activity and signaling processes. The dbPTM 2025 update significantly …