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Oestradiol as a neuromodulator of learning and memory
Although hormones such as glucocorticoids have been broadly accepted in recent decades
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
as general neuromodulators of memory processes, sex steroid hormones such as the potent …
Structural plasticity of the hippocampus in response to estrogens in female rodents
It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …
particular, estrogens modulate and mediate spine and synapse formation as well as …
Sex differences in the brain: Implications for behavioral and biomedical research
Biological differences between males and females are found at multiple levels. However,
females have too often been under-represented in behavioral neuroscience research, which …
females have too often been under-represented in behavioral neuroscience research, which …
[HTML][HTML] The role of estrogen in brain and cognitive aging
There are 3 common physiological estrogens, of which estradiol (E2) is seen to decline
rapidly over the menopausal transition. This decline in E2 has been associated with a …
rapidly over the menopausal transition. This decline in E2 has been associated with a …
A role for estrogen in schizophrenia: clinical and preclinical findings
Gender differences in schizophrenia have been extensively researched and it is being
increasingly accepted that gonadal steroids are strongly attributed to this phenomenon. Of …
increasingly accepted that gonadal steroids are strongly attributed to this phenomenon. Of …
Blockade of estrogen by hormonal contraceptives impairs fear extinction in female rats and women
BACKGROUND: Fear extinction is a laboratory model of fear inhibition and is the basis of
exposure therapy for anxiety disorders. Emerging evidence from naturally cycling female …
exposure therapy for anxiety disorders. Emerging evidence from naturally cycling female …
Sex differences in hippocampal function
Sex differences in the function of the hippocampus have been observed in numerous
mammalian species. However, the magnitude, extent, and specificity of these differences are …
mammalian species. However, the magnitude, extent, and specificity of these differences are …
Sex steroid hormones matter for learning and memory: estrogenic regulation of hippocampal function in male and female rodents
Ample evidence has demonstrated that sex steroid hormones, such as the potent estrogen
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …
17β-estradiol (E2), affect hippocampal morphology, plasticity, and memory in male and …
Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanisms.
BS McEwen, KT Akama, JL Spencer-Segal… - Behavioral …, 2012 - psycnet.apa.org
From its origins in how the brain controls the endocrine system via the hypothalamus and
pituitary gland, neuroendocrinology has evolved into a science that now includes hormone …
pituitary gland, neuroendocrinology has evolved into a science that now includes hormone …
Why estrogens matter for behavior and brain health
Abstract The National Institutes of Health (NIH) has required the inclusion of women in
clinical studies since 1993, which has enhanced our understanding of how biological sex …
clinical studies since 1993, which has enhanced our understanding of how biological sex …