Clinical practice guidelines are defined as ''systematically developed statements to assist
practitioner and patient decisions about appropriate heath care for specific clinical …

Anti-mitochondrial antibodies (AMA) are directed against the E2 subunits of the 2-oxo acid
dehydrogenase complexes (PDC-E2) and are the typical biomarkers of primary biliary …

Objective To assess the prevalence of clinical and biologic extrahepatic manifestations of
hepatitis C virus (HCV) infection and to identify associations between clinical and biologic …

Methods. ANA results vary widely depending on the substrate and immunohistochemical
methods used for detection. The technique most widely described in the current literature is …

Offering up-to-date, comprehensive coverage of disease progression, diagnosis,
management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference …

The cytochrome P450 proteins (CYPs) are a family of haem proteins resulting from
expression of a gene super-family that currently contains around 1000 members in species …

Autoimmune hepatitis is an uncommon idiopathic syndrome of immune-mediated
destruction of hepatocytes, typically associated with autoantibodies. The disease etiology is …

Randomized trials have shown the enhancement of efficacy with interferon alfa‐2b and
ribavirin (IFN‐R) in comparison with interferon monotherapy (IFN) as first line treatment of …

Infection with hepatitis C virus (HCV), a leading cause of chronic liver diseases, can
associate with B lymphocyte proliferative disorders, such as mixed cryoglobulinemia and …

The onset of peripheral ulcerative keratitis in the course of a connective tissue disorder, such
as rheumatoid arthritis, relapsing polychondritis, or systemic lupus erythematosus, may …