Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Diagnostics for neonatal sepsis: current approaches and future directions

PY Iroh Tam, CM Bendel - Pediatric research, 2017 - nature.com
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Mortality reduction by heart rate characteristic monitoring in very low birth weight neonates: a randomized trial

JR Moorman, WA Carlo, J Kattwinkel… - The Journal of …, 2011 - Elsevier
OBJECTIVE: To test the hypothesis that heart rate characteristics (HRC) monitoring
improves neonatal outcomes. STUDY DESIGN: We conducted a two-group, parallel …

Clinical microbiology of bacterial and fungal sepsis in very-low-birth-weight infants

D Kaufman, KD Fairchild - Clinical microbiology reviews, 2004 - journals.asm.org
Twenty percent of very-low-birth-weight (< 1500 g) preterm infants experience a serious
systemic infection, and despite advances in neonatal intensive care and antimicrobials …

Heart rate variability

G Ernst - 2014 - Springer
Organisms have rhythms, such as the rhythms of the cardiac and respiratory systems,
endocrinological networks, brain circuits, awake–sleep rhythms, and so on. All these …

Accurate estimation of entropy in very short physiological time series: the problem of atrial fibrillation detection in implanted ventricular devices

DE Lake, JR Moorman - American Journal of Physiology …, 2011 - journals.physiology.org
Entropy estimation is useful but difficult in short time series. For example, automated
detection of atrial fibrillation (AF) in very short heart beat interval time series would be useful …

Continuous vital sign analysis for predicting and preventing neonatal diseases in the twenty-first century: big data to the forefront

N Kumar, G Akangire, B Sullivan, K Fairchild… - Pediatric …, 2020 - nature.com
In the neonatal intensive care unit (NICU), heart rate, respiratory rate, and oxygen saturation
are vital signs (VS) that are continuously monitored in infants, while blood pressure is often …

Vital signs as physiomarkers of neonatal sepsis

BA Sullivan, KD Fairchild - Pediatric research, 2022 - nature.com
Neonatal sepsis accounts for significant morbidity and mortality, particularly among
premature infants in the Neonatal Intensive Care Unit. Abnormal vital sign patterns serve as …

Artificial intelligence and machine learning: Definition of terms and current concepts in critical care research

K Sun, A Roy, JM Tobin - Journal of Critical Care, 2024 - Elsevier
With increasing computing power, artificial intelligence (AI) and machine learning (ML) have
prospered, which facilitate the analysis of large datasets, especially those found in critical …

Heart rate characteristics: novel physiomarkers to predict neonatal infection and death

MP Griffin, DE Lake, EA Bissonette, FE Harrell Jr… - …, 2005 - publications.aap.org
Objective. Monitoring of regulated physiologic processes using physiomarkers such as heart
rate variability may be important in the early diagnosis of subacute, potentially catastrophic …