The recent recognition of a syndrome of tick‐acquired mammalian meat allergy has
transformed the previously held view that mammalian meat is an uncommon allergen. The …

Inflammatory bowel disease (IBD) is a group of disorders characterized by an inflammation
of the gastrointestinal tract (GIT) and represents a major social and economic burden …

Dengue has had a significant global health impact, with a dramatic increase in incidence
over the past 50 years, affecting more than 100 countries. The absence of a specific …

FGF/FGFR signaling is critical for the development and homeostasis of the human body and
imbalanced FGF/FGFR contributes to the progression of severe diseases, including cancers …

The gut immune system is shaped by the continuous interaction with the microbiota. Here
we dissect temporal, spatial and contextual layers of gut B cell responses. The microbiota …

Alpha-gal syndrome (AGS) describes a collection of symptoms associated with IgE-
mediated hypersensitivity responses to the glycan galactose-alpha-1, 3-galactose (alpha …

The α-gal epitope is a carbohydrate antigen which appeared early in mammalian evolution
and is synthesized in large amounts by the glycosylation enzyme α1, 3galactosyltransferase …

Interactions between humans and the gut microbiome occur by supplying nutrients to gut
epithelial cells via short-chain fatty acids obtained from dietary carbohydrates or mucins and …

Adaptation to environmental conditions occurs over diverse evolutionary timescales. In multi-
cellular organisms, adaptive traits are often studied in tissues/organs relevant to the …

The alpha-Gal epitope (α-Gal) with the determining element galactose-α1, 3-galactose can
lead to clinically relevant allergic reactions and rejections in xenotransplantation. These …