DNA base damage by reactive oxygen species, oxidizing agents, and UV radiation

J Cadet, JR Wagner - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
Emphasis has been placed in this article dedicated to DNA damage on recent aspects of the
formation and measurement of oxidatively generated damage in cellular DNA in order to …

Thirty Years of (TMS)3SiH: A Milestone in Radical-Based Synthetic Chemistry

C Chatgilialoglu, C Ferreri, Y Landais… - Chemical …, 2018 - ACS Publications
This review is an update on tris (trimethylsilyl) silane, TTMSS, in organic chemistry, focusing
on the advancements of the past decade. The overview includes a wide range of chemical …

Mechanisms of free radical-induced damage to DNA

M Dizdaroglu, P Jaruga - Free radical research, 2012 - Taylor & Francis
Endogenous and exogenous sources cause free radical-induced DNA damage in living
organisms by a variety of mechanisms. The highly reactive hydroxyl radical reacts with the …

Formation and repair of oxidatively generated damage in cellular DNA

J Cadet, KJA Davies, MHG Medeiros… - Free Radical Biology …, 2017 - Elsevier
In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

Targeting arginine methyltransferase PRMT5 for cancer therapy: updated progress and novel strategies

J Zheng, B Li, Y Wu, X Wu, Y Wang - Journal of Medicinal …, 2023 - ACS Publications
As a predominant type II protein arginine methyltransferase, PRMT5 plays critical roles in
various normal cellular processes by catalyzing the mono-and symmetrical dimethylation of …

Oxidatively induced DNA damage and its repair in cancer

M Dizdaroglu - Mutation Research/Reviews in Mutation Research, 2015 - Elsevier
Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Occurrence, biological consequences, and human health relevance of oxidative stress-induced DNA damage

Y Yu, Y Cui, LJ Niedernhofer… - Chemical research in …, 2016 - ACS Publications
A variety of endogenous and exogenous agents can induce DNA damage and lead to
genomic instability. Reactive oxygen species (ROS), an important class of DNA damaging …

1,n‐Hydrogen‐Atom Transfer (HAT) Reactions in Which n≠5: An Updated Inventory

M Nechab, S Mondal… - Chemistry–A European …, 2014 - Wiley Online Library
Hydrogen‐atom transfer (HAT) counts amongst the most widely investigated routes to
carbon‐centered radicals. Intramolecular processes involving 1, 5‐HAT are widespread to …

Direct and indirect chemiluminescence: reactions, mechanisms and challenges

MA Tzani, DK Gioftsidou, MG Kallitsakis, NV Pliatsios… - Molecules, 2021 - mdpi.com
Emission of light by matter can occur through a variety of mechanisms. When it results from
an electronically excited state of a species produced by a chemical reaction, it is called …

Oxidatively generated complex DNA damage: tandem and clustered lesions

J Cadet, JL Ravanat, M TavernaPorro, H Menoni… - Cancer letters, 2012 - Elsevier
There is an increasing interest for oxidatively generated complex lesions that are potentially
more detrimental than single oxidized nucleobases. In this survey, the recently available …