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Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder
N Usui, H Kobayashi, S Shimada - International journal of molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …
impairments in social communication, repetitive behaviors, restricted interests, and …
Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109)
L Chen, XJ Shi, H Liu, X Mao, LN Gui, H Wang… - Translational …, 2021 - nature.com
There is increasing awareness that oxidative stress may be implicated in the
pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood …
pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood …
[HTML][HTML] High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways
Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
Fragile X messenger ribonucleoprotein 1 protein (FMRP) deficiency leads to fragile X
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
syndrome (FXS), an autism spectrum disorder. The role of FMRP in prenatal human brain …
The role of glutathione redox imbalance in autism spectrum disorder: A review
G Bjørklund, AA Tinkov, B Hosnedlová, R Kizek… - Free Radical Biology …, 2020 - Elsevier
The role of glutathione in autism spectrum disorder (ASD) is emerging as a major topic, due
to its role in the maintenance of the intracellular redox balance. Several studies have …
to its role in the maintenance of the intracellular redox balance. Several studies have …
Mitochondria, metabolism, and redox mechanisms in psychiatric disorders
Significance: Our current knowledge of the pathophysiology and molecular mechanisms
causing psychiatric disorders is modest, but genetic susceptibility and environmental factors …
causing psychiatric disorders is modest, but genetic susceptibility and environmental factors …
Mitochondrial, exosomal miR137-COX6A2 and gamma synchrony as biomarkers of parvalbumin interneurons, psychopathology, and neurocognition in schizophrenia
I Khadimallah, R Jenni, JH Cabungcal, M Cleusix… - Molecular …, 2022 - nature.com
Early detection and intervention in schizophrenia requires mechanism-based biomarkers
that capture neural circuitry dysfunction, allowing better patient stratification, monitoring of …
that capture neural circuitry dysfunction, allowing better patient stratification, monitoring of …
Mitochondrial protein biogenesis in the synapse is supported by local translation
B Kuzniewska, D Cysewski, M Wasilewski… - EMBO …, 2020 - embopress.org
Synapses are the regions of the neuron that enable the transmission and propagation of
action potentials on the cost of high energy consumption and elevated demand for …
action potentials on the cost of high energy consumption and elevated demand for …
[HTML][HTML] Folic acid and autism: a systematic review of the current state of knowledge
Folic acid has been identified to be integral in rapid tissue growth and cell division during
fetal development. Different studies indicate folic acid's importance in improving childhood …
fetal development. Different studies indicate folic acid's importance in improving childhood …
[HTML][HTML] The pathophysiological role of CoA
A Czumaj, S Szrok-Jurga, A Hebanowska… - International Journal of …, 2020 - mdpi.com
The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …