The K = 2 conundrum
Assessments of population genetic structure have become an increasing focus as they can
provide valuable insight into patterns of migration and gene flow. structure, the most highly …
provide valuable insight into patterns of migration and gene flow. structure, the most highly …
Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow
Speciation, the evolution of reproductive isolation among populations, is continuous,
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …
Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power
Admixed populations are routinely excluded from genomic studies due to concerns over
population structure. Here, we present a statistical framework and software package, Tractor …
population structure. Here, we present a statistical framework and software package, Tractor …
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference
Local-ancestry inference is an important step in the genetic analysis of fully sequenced
human genomes. Current methods can only detect continental-level ancestry (ie, European …
human genomes. Current methods can only detect continental-level ancestry (ie, European …
The politics of life itself
N Rose - Theory, culture & society, 2001 - journals.sagepub.com
This article explores contemporary biopolitics in the light of Michel Foucault's oft quoted
suggestion that contemporary politics callslife itself'into question. It suggests that recent …
suggestion that contemporary politics callslife itself'into question. It suggests that recent …
Population structure and eigenanalysis
N Patterson, AL Price, D Reich - PLoS genetics, 2006 - journals.plos.org
Current methods for inferring population structure from genetic data do not provide formal
significance tests for population differentiation. We discuss an approach to studying …
significance tests for population differentiation. We discuss an approach to studying …
Genome-wide association studies for common diseases and complex traits
Genetic factors strongly affect susceptibility to common diseases and also influence disease-
related quantitative traits. Identifying the relevant genes has been difficult, in part because …
related quantitative traits. Identifying the relevant genes has been difficult, in part because …
Genome-wide association studies in diverse populations
NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …
associated with disease phenotypes. As most GWA studies have been performed in …
[HTML][HTML] Modeling 3D facial shape from DNA
P Claes, DK Liberton, K Daniels, KM Rosana… - PLoS …, 2014 - journals.plos.org
Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …
used spatially dense quasi-landmarks to measure face shape in population samples with …
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations
AL Price, A Tandon, N Patterson, KC Barnes… - PLoS …, 2009 - journals.plos.org
Identifying the ancestry of chromosomal segments of distinct ancestry has a wide range of
applications from disease map** to learning about history. Most methods require the use …
applications from disease map** to learning about history. Most methods require the use …