The K = 2 conundrum

JK Janes, JM Miller, JR Dupuis… - Molecular …, 2017 - Wiley Online Library
Assessments of population genetic structure have become an increasing focus as they can
provide valuable insight into patterns of migration and gene flow. structure, the most highly …

Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow

M Ravinet, R Faria, RK Butlin, J Galindo… - Journal of …, 2017 - academic.oup.com
Speciation, the evolution of reproductive isolation among populations, is continuous,
complex, and involves multiple, interacting barriers. Until it is complete, the effects of this …

Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power

EG Atkinson, AX Maihofer, M Kanai, AR Martin… - Nature …, 2021 - nature.com
Admixed populations are routinely excluded from genomic studies due to concerns over
population structure. Here, we present a statistical framework and software package, Tractor …

RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference

BK Maples, S Gravel, EE Kenny… - The American Journal of …, 2013 - cell.com
Local-ancestry inference is an important step in the genetic analysis of fully sequenced
human genomes. Current methods can only detect continental-level ancestry (ie, European …

The politics of life itself

N Rose - Theory, culture & society, 2001 - journals.sagepub.com
This article explores contemporary biopolitics in the light of Michel Foucault's oft quoted
suggestion that contemporary politics callslife itself'into question. It suggests that recent …

Population structure and eigenanalysis

N Patterson, AL Price, D Reich - PLoS genetics, 2006 - journals.plos.org
Current methods for inferring population structure from genetic data do not provide formal
significance tests for population differentiation. We discuss an approach to studying …

Genome-wide association studies for common diseases and complex traits

JN Hirschhorn, MJ Daly - Nature reviews genetics, 2005 - nature.com
Genetic factors strongly affect susceptibility to common diseases and also influence disease-
related quantitative traits. Identifying the relevant genes has been difficult, in part because …

Genome-wide association studies in diverse populations

NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …

[HTML][HTML] Modeling 3D facial shape from DNA

P Claes, DK Liberton, K Daniels, KM Rosana… - PLoS …, 2014 - journals.plos.org
Human facial diversity is substantial, complex, and largely scientifically unexplained. We
used spatially dense quasi-landmarks to measure face shape in population samples with …

Sensitive detection of chromosomal segments of distinct ancestry in admixed populations

AL Price, A Tandon, N Patterson, KC Barnes… - PLoS …, 2009 - journals.plos.org
Identifying the ancestry of chromosomal segments of distinct ancestry has a wide range of
applications from disease map** to learning about history. Most methods require the use …