Necrotizing Soft-Tissue Infections | New England Journal of Medicine Skip to main content
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Importance Cellulitis is an infection of the deep dermis and subcutaneous tissue, presenting
with expanding erythema, warmth, tenderness, and swelling. Cellulitis is a common global …

Necrotizing soft-tissue infections (NSTIs) are highly lethal. They are frequent enough that
general and specialty physicians will likely have to be involved with the management of at …

Necrotizing soft-tissue infection (NSTI) was first described by Hippocrates circa 500 BC,
when he wrote,“Many were attacked by the erysipelas all over the body when the exciting …

Delayed recognition, with consequent massive soft tissue loss and sepsis, remains a deadly
pitfall in the management of necrotizing fasciitis. With a better understanding of the clinical …

Background Cervical necrotizing fasciitis is a progressive soft tissue infection with significant
morbidity and mortality. Methods A case review of cervical necrotizing fasciitis managed at …

Objective: In 2003, critical care and infectious disease experts representing 11 international
organizations developed management guidelines for source control in the management of …

Objectives: Descending necrotizing mediastinitis is a polymicrobial infection originating in
the oropharynx with previously reported mortality rates of 25% to 40%. This investigation …

The purpose of this article is to review currently used imaging protocols for the evaluation of
pathologic conditions of the larynx and hypopharynx, to describe key anatomic structures in …

Background Necrotizing fasciitis is a severe soft‐tissue infection characterized by a
fulminant course and high mortality. Early recognition is difficult as the disease is often …