Recently, the co-crystallization of pharmaceutical drugs is gaining consideration because it
is an environmentally friendly and potentially effective technique to improve the solubility …

Alzheimer's disease (AD) is a neurodegenerative disease that affects a wide range of
populations and is the primary cause of death in various countries. The treatment of AD is …

Antifungal therapy is causing an alarming drug resistance problem during the treatment of
Vaginal Candidiasis and also many of the antifungal vaginal marketed formulations have …

Abstract Purpose Posaconazole (PSZ) is BCS class-II drug that displays variable
bioavailability upon oral administration due to extremely low and pH-dependent solubility …

Solubility is a critical factor for the therapeutic action of drugs and does not depend on the
administration of routes. Various conventional methods are used to enhance the solubility of …

Liquisolid systems (LS) represent a formulation approach where liquid drug or its dispersion
is transformed into a powder with good flowability and compactibility, leading to enhanced …

Continuous manufacturing is becoming the new technological standard in the
pharmaceutical industry. In this work, a twin-screw processor was employed for the …

Background In the pharmaceutical sciences, the solubility profile of therapeutic molecules is
crucial for identifying and formulating drugs and evaluating their quality across the drug …

Increasing influx of poorly water-soluble drugs poses a significant challenge to oral drug
delivery. Conventional solubilization techniques such as solid dispersion and cyclodextrin …

Poor aqueous solubility and slow dissolution rate adversely affect the bioavailability of
ibuprofen. The purpose of the investigation was to develop and evaluate liquisolid compact …