[HTML][HTML] Bioactivity and therapeutic potential of kaempferol and quercetin: new insights for plant and human health

R Jan, M Khan, S Asaf, Lubna, S Asif, KM Kim - Plants, 2022 - mdpi.com
Plant secondary metabolites, especially flavonoids, are major metabolites widely found in
plants that play several key roles in plant defence and signalling in response to stress …

[HTML][HTML] Potential pharmaceutical applications of quercetin in cardiovascular diseases

P Papakyriakopoulou, N Velidakis, E Khattab… - Pharmaceuticals, 2022 - mdpi.com
Quercetin, as a member of flavonoids, has emerged as a potential therapeutic agent in
cardiovascular diseases (CVDs) in recent decades. In this comprehensive literature review …

Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer's disease model

P Zhang, Y Kishimoto, I Grammatikakis… - Nature …, 2019 - nature.com
Neuritic plaques, a pathological hallmark in Alzheimer's disease (AD) brains, comprise
extracellular aggregates of amyloid-beta (Aβ) peptide and degenerating neurites that …

Quercetin attenuates cerebral ischemic injury by inhibiting ferroptosis via Nrf2/HO-1 signaling pathway

C Peng, Q Ai, F Zhao, H Li, Y Sun, K Tang… - European Journal of …, 2024 - Elsevier
Aims Ischemic stroke is a severe cerebrovascular disease in which neuronal death
continually occurs through multiple forms, including apoptosis, autophagy, pyroptosis and …

Unraveling the therapeutic potential of quercetin and quercetin-3-O-glucuronide in Alzheimer's disease through network pharmacology, molecular docking, and …

S Sabarathinam - Scientific Reports, 2024 - nature.com
Quercetin is a flavonoid with notable pharmacological effects and promising therapeutic
potential. Quercetin plays a significant role in neuroinflammation, which helps reduce …

[HTML][HTML] Anti-inflammatory, antioxidant, moisturizing, and antimelanogenesis effects of quercetin 3-O-β-D-glucuronide in human keratinocytes and melanoma cells via …

AT Ha, L Rahmawati, L You, MA Hossain… - International Journal of …, 2021 - mdpi.com
Quercetin 3-O-β-D-glucuronide (Q-3-G), the glucuronide conjugate of quercetin, has been
reported as having anti-inflammatory properties in the lipopolysaccharide-stimulated …

Protective effects of dietary quercetin on cerebral ischemic injury: pharmacology, pharmacokinetics and bioavailability-enhancing nanoformulations

Y Zhang, K Fu, C Wang, C Ma, L Gong, H Zhou… - Food & function, 2023 - pubs.rsc.org
Cerebral ischemia, as an ischemic stroke-like disease, has become a health problem of
global concern. Studies have found that oxidative stress, inflammation, apoptosis, and …

Green approaches for the extraction of antioxidants from eucalyptus leaves

B Gullon, A Muniz-Mouro, TA Lu-Chau… - Industrial Crops and …, 2019 - Elsevier
Leaf extracts of Eucalyptus globulus present a wide range of phenolic compounds with
interest in the pharmaceutical, health, agricultural, cosmetic and food industries because of …

[HTML][HTML] A Systematic Review: Quercetin—Secondary Metabolite of the Flavonol Class, with Multiple Health Benefits and Low Bioavailability

OD Frenț, L Stefan, CM Morgovan… - International …, 2024 - pmc.ncbi.nlm.nih.gov
The main goal of this systematic review on the flavonol class secondary metabolite quercetin
is to evaluate and summarize the existing research on quercetin's potential health benefits …

Revealing the potential bioactive components and mechanism of Qianhua Gout Capsules in the treatment of gouty arthritis through network pharmacology, molecular …

G **ang, L Yang, J Qin, S Wang, Y Zhang, S Yang - Heliyon, 2024 - cell.com
Recent clinical studies have confirmed the effectiveness of Qianhua Gout Capsules (QGC)
in the treatment of gouty arthritis (GA). However, the specific regulatory targets and …