Exosome-based macromolecular neurotherapeutic drug delivery approaches in overcoming the blood-brain barrier for treating brain disorders

K Yadav, R Vijayalakshmi, KK Sahu, P Sure… - European Journal of …, 2024 - Elsevier
Delivering drugs to the brain is a complex challenge in medical research, particularly for
disorders like Alzheimer's and Parkinson's. The blood–brain barrier restricts the entry of …

Comprehensive overview of controlled fabrication of multifunctional fluorescent carbon quantum dots and exploring applications

L Yang, Y An, D Xu, F Dai, S Shao, Z Lu, G Liu - Small, 2024 - Wiley Online Library
In recent years, carbon dots (CDs) have garnered increasing attention due to their simple
preparation methods, versatile performances, and wide‐ranging applications. CDs can …

Synthesis of antibacterial fluorescent carbon dots and green coal-like hydrochar from tea Industry byproducts via hydrothermal carbonization

P Duarah, B Debnath, MK Purkait - Industrial Crops and Products, 2024 - Elsevier
This study introduces an experimental framework employing hydrothermal carbonization
(HTC) for the valorisation of factory tea waste as a solid fuel. Employing a centre composite …

A Review: Surface Engineering of Lipid‐Based Drug Delivery Systems

D Patel, J Solanki, MM Kher, A Azagury - Small, 2024 - Wiley Online Library
This review explores the evolution of lipid‐based nanoparticles (LBNPs) for drug delivery
(DD). Herein, LBNPs are classified into liposomes and cell membrane‐based nanoparticles …

Exploring nanocarriers as innovative materials for advanced drug delivery strategies in onco-immunotherapies

P Tiwari, RP Shukla, K Yadav, D Panwar… - Journal of Molecular …, 2024 - Elsevier
In recent years, Onco-immunotherapies (OIMTs) have been shown to be a potential therapy
option for cancer. Several immunotherapies have received regulatory approval, while many …

Cell membrane-coated nanoparticles for precision medicine: a comprehensive review of coating techniques for tissue-specific therapeutics

A Fernández-Borbolla, L García-Hevia… - International Journal of …, 2024 - mdpi.com
Nanoencapsulation has become a recent advancement in drug delivery, enhancing stability,
bioavailability, and enabling controlled, targeted substance delivery to specific cells or …

[HTML][HTML] A complex molecular landscape to drug delivery concept for achieving precise therapy in psoriasis

K Yadav, KK Sahu, R Yadav, W Raza, S Minz… - Medicine in Drug …, 2024 - Elsevier
Psoriasis is a chronic autoimmune disorder that has a major effect on the quality of life for
millions of people throughout the world. The pathogenesis of psoriasis has revealed intricate …

Engineering exosomes to reshape the immune microenvironment in breast cancer: Molecular insights and therapeutic opportunities

J Cao, G Lv, F Wei - Clinical and Translational Medicine, 2024 - Wiley Online Library
Background Breast cancer remains a global health challenge, necessitating innovative
therapeutic approaches. Immunomodulation and immunotherapy have emerged as …

Nano revolution of DNA nanostructures redefining cancer therapeutics—A comprehensive review

K Yadav, SPE Gnanakani, KK Sahu, CK Veni… - International Journal of …, 2024 - Elsevier
DNA nanostructures are a promising tool in cancer treatment, offering an innovative way to
improve the effectiveness of therapies. These nanostructures can be made solely from DNA …

Celastrol-loaded polymeric mixed micelles shows improved antitumor efficacy in 4 T1 bearing xenograft mouse model through spatial targeting

S Gautam, N Singh, D Marwaha, N Rai… - International Journal of …, 2024 - Elsevier
In this study, we have proposed a novel approach that combines hyaluronic acid (HA), folic
acid (FA), and celastrol (CLS) within a polymeric micelle system (CLS-HF/MLs), offering a …