[HTML][HTML] DNA methylation and microRNA dysregulation in cancer
H Suzuki, R Maruyama, E Yamamoto, M Kai - Molecular oncology, 2012 - Elsevier
DNA methylation plays a key role in the silencing of numerous cancer-related genes,
thereby affecting a number of vital cellular processes, including the cell cycle checkpoint …
thereby affecting a number of vital cellular processes, including the cell cycle checkpoint …
The emerging role of miR‐375 in cancer
MicroRNAs (miRNAs) are evolutionarily conserved, small noncoding RNAs that are believed
to play fundamental roles in various biological processes through regulation of gene …
to play fundamental roles in various biological processes through regulation of gene …
Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma
L Zhang, FU Yang, J Yuan, S Yuan, W Zhou… - …, 2013 - academic.oup.com
Although numerous long non-coding RNAs (lncRNAs) have been identified in mammals,
many of their biological roles remain to be characterized. Early reports suggest that H19 …
many of their biological roles remain to be characterized. Early reports suggest that H19 …
circKIF4A acts as a prognostic factor and mediator to regulate the progression of triple-negative breast cancer
Background Increasing studies has found that circular RNAs (circRNAs) play vital roles in
cancer progression. But the expression profile and function of circRNAs in triple-negative …
cancer progression. But the expression profile and function of circRNAs in triple-negative …
Predictive role of plasmatic biomarkers in advanced non-small cell lung cancer treated by nivolumab
A Costantini, C Julie, C Dumenil… - …, 2018 - Taylor & Francis
Immune checkpoint inhibitors, as nivolumab, are used in advanced non-small cell lung
cancer (NSCLC). However, no associated biomarker is validated in clinical practice with this …
cancer (NSCLC). However, no associated biomarker is validated in clinical practice with this …
Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
Epithelial–mesenchymal transition (EMT) is an initiating event in tumor cell invasion and
metastasis. It has been shown to occur in resistance to a range of cancer therapies …
metastasis. It has been shown to occur in resistance to a range of cancer therapies …
Genomic and epigenomic aberrations in esophageal squamous cell carcinoma and implications for patients
DC Lin, MR Wang, HP Koeffler - Gastroenterology, 2018 - Elsevier
Esophageal squamous cell carcinoma (ESCC) is a common malignancy without effective
therapy. The exomes of more than 600 ESCCs have been sequenced in the past 4 years …
therapy. The exomes of more than 600 ESCCs have been sequenced in the past 4 years …
Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases
Allergic inflammation is accompanied by the coordinated expression of a myriad of genes
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …
miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis
Abstract miR-375 is a tumor-suppressive microRNA (miRNA) in gastric cancer (GC).
However, its molecular mechanism remains unclear. The aim of this study is to …
However, its molecular mechanism remains unclear. The aim of this study is to …
MicroRNA‐375‐3p enhances chemosensitivity to 5‐fluorouracil by targeting thymidylate synthase in colorectal cancer
F Xu, ML Ye, YP Zhang, WJ Li, MT Li, HZ Wang… - Cancer …, 2020 - Wiley Online Library
Resistance to chemotherapy is a major challenge for the treatment of patients with colorectal
cancer (CRC). Previous studies have found that microRNAs (miRNAs) play key roles in drug …
cancer (CRC). Previous studies have found that microRNAs (miRNAs) play key roles in drug …