The gut microbiome in neurological disorders

JF Cryan, KJ O'Riordan, K Sandhu, V Peterson… - The Lancet …, 2020 - thelancet.com
Research into the role of the gut microbiome in modulating brain function has rapidly
increased over the past 10 years, albeit chiefly in animal models. Increasing clinical and …

The microbiota-gut-brain axis

JF Cryan, KJ O'Riordan, CSM Cowan… - Physiological …, 2019 - journals.physiology.org
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice

G Sharon, NJ Cruz, DW Kang, MJ Gandal, B Wang… - Cell, 2019 - cell.com
Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors
including social communication and stereotypies. In addition to genetic risks, the gut …

Stress & the gut-brain axis: regulation by the microbiome

JA Foster, L Rinaman, JF Cryan - Neurobiology of stress, 2017 - Elsevier
The importance of the gut–brain axis in regulating stress-related responses has long been
appreciated. More recently, the microbiota has emerged as a key player in the control of this …

[HTML][HTML] The central nervous system and the gut microbiome

G Sharon, TR Sampson, DH Geschwind… - Cell, 2016 - cell.com
Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

Transferring the blues: depression-associated gut microbiota induces neurobehavioural changes in the rat

JR Kelly, Y Borre, C O'Brien, E Patterson… - Journal of psychiatric …, 2016 - Elsevier
The gut microbiota interacts with the host via neuroimmune, neuroendocrine and neural
pathways. These pathways are components of the brain-gut-microbiota axis and preclinical …

Autism spectrum disorders and the gut microbiota

A Fattorusso, L Di Genova, GB Dell'Isola, E Mencaroni… - Nutrients, 2019 - mdpi.com
In recent years, there has been an emerging interest in the possible role of the gut
microbiota as a co-factor in the development of autism spectrum disorders (ASDs), as many …

Targeting the microbiota-gut-brain axis: prebiotics have anxiolytic and antidepressant-like effects and reverse the impact of chronic stress in mice

A Burokas, S Arboleya, RD Moloney, VL Peterson… - Biological …, 2017 - Elsevier
Background The realization that the microbiota-gut-brain axis plays a critical role in health
and disease, including neuropsychiatric disorders, is rapidly advancing. Nurturing a …

[HTML][HTML] Gut microbiota and the neuroendocrine system

A Farzi, EE Fröhlich, P Holzer - Neurotherapeutics, 2018 - Elsevier
The microbial ecosystem that inhabits the gastrointestinal tract of all mammals—the gut
microbiota—has been in a symbiotic relationship with its hosts over many millennia. Thanks …

Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration

TG Dinan, JF Cryan - The Journal of physiology, 2017 - Wiley Online Library
There is a growing realisation that the gut–brain axis and its regulation by the microbiota
may play a key role in the biological and physiological basis of neurodevelopmental, age …