Abstract Background Pentavalent antimonials (Sb (V)) such as meglumine antimoniate
(Glucantime®) and sodium stibogluconate (Pentostam®) are used as first‐line treatments for …

Glycolysis and glyconeogenesis play crucial roles in the ATP supply and synthesis of
glycoconjugates, important for the viability and virulence, respectively, of the human …

Pathogens have developed particular strategies to infect and invade their hosts. Amongst
these strategies' figures the modulation of several components of the innate immune system …

The interaction of pathogenic bacteria with the host fibrinolytic system through the
plasminogen molecule has been well documented. It has been shown, using animal …

Plasmin is the final product of the fibrinolytic system, the physiological mechanism
responsible for dissolving fibrin clots. Its broad-range proteolytic activity implies that …

A leishmaniose é uma doença negligenciada que possui a grande maioria dos casos
registrados em países subdesenvolvidos e assim como outras doenças negligenciadas …

Visceral leishmaniasis (VL) is a tropical infectious disease, which is called Mediterranean
visceral leishmaniasis (MVL) in the Mediterranean area. In spite of many attempts, no …

Plasmodium and other vector-borne pathogens have evolved mechanisms to hijack the
mammalian fibrinolytic system to facilitate infection of the human host and the invertebrate …

Membrane vesicles secreted by Leishmania mexicana were collected and analyzed. These
vesicles can bind plasminogen and were shown to contain enolase, previously identified as …

The genus Perkinsus includes protozoan parasites of a wide range of marine molluscs
worldwide, some of which have been responsible for heavy mollusc mortalities and dramatic …