In the mammalian genome, DNA methylation is an epigenetic mechanism involving the
transfer of a methyl group onto the C5 position of the cytosine to form 5-methylcytosine. DNA …

The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …

Exposure of develo** male germ cells to environmental insults has been linked to adverse
effects in the offspring. One mechanism by which germ cell defects may be passed …

DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

Objective To characterize a potential genetic cause for methylation errors described in
oligozoospermia. Design Analysis of PEG1/MEST-DMR and H19-DMR methylation level in …

Hybrid dysfunction, a common feature of reproductive barriers between species, is often
caused by negative epistasis between loci (“Dobzhansky-Muller incompatibilities”). The …

The influence of aberrant sperm DNA methylation on the reproductive capacity of couples
has been postulated as a cause of infertility. This study compared the DNA methylation of …

Assisted reproductive technologies (ART) account for 1–6% of births in developed countries.
While most children conceived are healthy, increases in birth and genomic imprinting …

Background Paternal obesity has been associated with reduced live birth rates. It could lead
to inheritance of metabolic disturbances to the offspring through epigenetic mechanisms …

The phenomenon of male sterility in interspecies hybrids has been observed for over a
century, however, few genes influencing this recurrent phenotype have been identified …