Accurate detection of identity-by-descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick, I Olalde… - Nature …, 2024 - nature.com
Long DNA segments shared between two individuals, known as identity-by-descent (IBD),
reveal recent genealogical connections. Here we introduce ancIBD, a method for identifying …

The genomic history of the indigenous people of the Canary Islands

JG Serrano, AC Ordóñez, J Santana… - Nature …, 2023 - nature.com
The indigenous population of the Canary Islands, which colonized the archipelago around
the 3rd century CE, provides both a window into the past of North Africa and a unique model …

Reconstruction of the human amylase locus reveals ancient duplications seeding modern-day variation

F Yilmaz, C Karageorgiou, K Kim, P Pajic, K Scheer… - Science, 2024 - science.org
Previous studies suggested that the copy number of the human salivary amylase gene,
AMY1, correlates with starch-rich diets. However, evolutionary analyses are hampered by …

A high-coverage mesolithic aurochs genome and effective leveraging of ancient cattle genomes using whole genome imputation

JAM Erven, A Scheu, MP Verdugo… - Molecular Biology …, 2024 - academic.oup.com
Ancient genomic analyses are often restricted to utilizing pseudohaploid data due to low
genome coverage. Leveraging low-coverage data by imputation to calculate phased diploid …

ancIBD-Screening for identity by descent segments in human ancient DNA

H Ringbauer, Y Huang, A Akbari, S Mallick… - BioRxiv, 2023 - pmc.ncbi.nlm.nih.gov
Long DNA sequences shared between two individuals, known as Identical by descent (IBD)
segments, are a powerful signal for identifying close and distant biological relatives because …

The genetics of the inhabitants of Neolithic Britain: a review

S Brace, T Booth - Ancient DNA and the European Neolithic …, 2023 - books.google.com
This chapter aims to review studies of the genetics of the inhabitants of Mesolithic and
Neolithic Britain from the late 5th to the end of the 3rd millennium cal BC. We lay out the …

Pervasive findings of directional selection realize the promise of ancient DNA to elucidate human adaptation

A Akbari, AR Barton, S Gazal, Z Li, M Kariminejad… - …, 2024 - pmc.ncbi.nlm.nih.gov
We present a method for detecting evidence of natural selection in ancient DNA time-series
data that leverages an opportunity not utilized in previous scans: testing for a consistent …

[HTML][HTML] Genetic landscape of ALS in Malta based on a quinquennial analysis

MF Wismayer, AF Wismayer, R Borg, K Bonavia… - Neurobiology of …, 2023 - Elsevier
Genetic risk for amyotrophic lateral sclerosis (ALS) is highly elevated in genetic isolates, like
the island population of Malta in the south of Europe, providing a unique opportunity to …

Interbreeding between farmers and hunter-gatherers along the inland and Mediterranean routes of Neolithic spread in Europe

J Fort, J Pérez-Losada - Nature Communications, 2024 - nature.com
The Neolithic (ie, farming and stockbreeding) spread from the Near East across Europe
since about 9000 years before the common era (BCE) until about 4000 yr BCE. It followed …

Medieval DNA from Soqotra points to Eurasian origins of an isolated population at the crossroads of Africa and Arabia

K Sirak, J Jansen Van Rensburg, E Brielle… - Nature ecology & …, 2024 - nature.com
Soqotra, an island situated at the mouth of the Gulf of Aden in the northwest Indian Ocean
between Africa and Arabia, is home to~ 60,000 people subsisting through fishing and semi …