Colorectal cancer (CRC) is one of the most frequently occurring malignancy tumors with a
high morbidity additionally, CRC patients may develop liver metastasis, which is the major …

A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a
significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF …

Transforming growth factor-beta (TGF-β) signaling is one of the important cellular pathways
that play key roles for tissue maintenance. In particular, it is important in the context of …

Colorectal cancer (CRC) represents the third most commonly diagnosed cancer and the
second leading cause of cancer death worldwide. The modern concept of cancer biology …

Colorectal cancer (CRC) is a serious public health issue, and it has the leading incidence
and mortality among malignant tumors worldwide. CRC patients with metastasis in the liver …

Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Background Emerging evidences have indicated that long non-coding RNAs (lncRNAs) play
vital roles in cardiovascular physiology and pathology. The lncRNA MALAT1, a highly …

Abstract Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase that participates
in an array of critical cellular processes. GSK-3 was first characterized as an enzyme that …

MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …