Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

As the gap between donors and patients in need of an organ transplant continues to widen,
research in regenerative medicine seeks to provide alternative strategies for treatment. One …

Tremendous progress has been achieved in the field of tissue engineering in the past
decade. Several major challenges laid down 10 years ago, have been studied, including …

Organ and tissue loss through disease and injury motivate the development of therapies that
can regenerate tissues and decrease reliance on transplantations. Regenerative medicine …

Extracellular matrix (ECM) collectively represents a class of naturally derived proteinaceous
biomaterials purified from harvested organs and tissues with increasing scientific focus and …

Extracellular matrix (ECM) plays an important developmental role by regulating cell
behaviour through structural and biochemical stimulation. Tissue-specific ECM, attained …

Natural biomaterials are extensively used in tissue engineering due to their microstructure
interconnectivity and inherent bioactivity which mimics of natural extracellular matrix (ECM) …

Insulin remains indispensable in the treatment of diabetes, but its use is hampered by its
narrow therapeutic index. Although advances in peptide chemistry and recombinant DNA …

The native extracellular matrix (ECM) outlines the architecture of organs and tissues. It
provides a unique niche of composition and form, which serves as a foundational scaffold …

With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …