The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

The gut virome: A new microbiome component in health and disease

Z Cao, N Sugimura, E Burgermeister, MP Ebert… - …, 2022 - thelancet.com
The human gastrointestinal tract harbours an abundance of viruses, collectively known as
the gut virome. The gut virome is highly heterogeneous across populations and is linked to …

Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome

S Nayfach, D Páez-Espino, L Call, SJ Low… - Nature …, 2021 - nature.com
Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …

Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

Phage diversity, genomics and phylogeny

MB Dion, F Oechslin, S Moineau - Nature Reviews Microbiology, 2020 - nature.com
Recent advances in viral metagenomics have enabled the rapid discovery of an
unprecedented catalogue of phages in numerous environments, from the human gut to the …

Gut microbiome, liver immunology, and liver diseases

R Wang, R Tang, B Li, X Ma, B Schnabl… - Cellular & molecular …, 2021 - nature.com
The gut microbiota is a complex and plastic consortium of microorganisms that are intricately
connected with human physiology. The liver is a central immunological organ that is …

A catalog of tens of thousands of viruses from human metagenomes reveals hidden associations with chronic diseases

MJ Tisza, CB Buck - … of the National Academy of Sciences, 2021 - National Acad Sciences
Despite remarkable strides in microbiome research, the viral component of the microbiome
has generally presented a more challenging target than the bacteriome. This gap persists …

The human gut virome is highly diverse, stable, and individual specific

AN Shkoporov, AG Clooney, TDS Sutton, FJ Ryan… - Cell host & …, 2019 - cell.com
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in sha** the gut microbiome and in impacting on human …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

Gut microbiota and IBD: causation or correlation?

J Ni, GD Wu, L Albenberg, VT Tomov - Nature reviews Gastroenterology …, 2017 - nature.com
A general consensus exists that IBD is associated with compositional and metabolic
changes in the intestinal microbiota (dysbiosis). However, a direct causal relationship …