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Molecular physiology and pathophysiology of bilirubin handling by the blood, liver, intestine, and brain in the newborn
Bilirubin is the end product of heme catabolism formed during a process that involves
oxidation-reduction reactions and conserves iron body stores. Unconjugated …
oxidation-reduction reactions and conserves iron body stores. Unconjugated …
A novel perspective on the biology of bilirubin in health and disease
Unconjugated bilirubin (UCB) is known to be one of the most potent endogenous antioxidant
substances. While hyperbilirubinemia has long been recognized as an ominous sign of liver …
substances. While hyperbilirubinemia has long been recognized as an ominous sign of liver …
Guidelines on the management of abnormal liver blood tests
These updated guidelines on the management of abnormal liver blood tests have been
commissioned by the Clinical Services and Standards Committee (CSSC) of the British …
commissioned by the Clinical Services and Standards Committee (CSSC) of the British …
Bilirubin nanoparticles as a nanomedicine for anti‐inflammation therapy
Despite the high potency of bilirubin as an endogenous anti‐inflammatory compound, its
clinical translation has been hampered because of its insolubility in water. Bilirubin‐based …
clinical translation has been hampered because of its insolubility in water. Bilirubin‐based …
Looking to the horizon: the role of bilirubin in the development and prevention of age-related chronic diseases
Bilirubin, the principal tetrapyrrole, bile pigment and catabolite of haem, is an emerging
biomarker of disease resistance, which may be related to several recently documented …
biomarker of disease resistance, which may be related to several recently documented …
Oxidative theory of atherosclerosis and antioxidants
Atherosclerosis is a multifactorial process that begins early in infancy and affects all the
humans. Early steps of atherogenesis and the evolution towards complex atherosclerotic …
humans. Early steps of atherogenesis and the evolution towards complex atherosclerotic …
Bilirubin nanomedicines for the treatment of reactive oxygen species (ROS)-mediated diseases
Reactive oxygen species (ROS) are chemically reactive species that are produced in
cellular aerobic metabolism. They mainly include superoxide anion, hydrogen peroxide …
cellular aerobic metabolism. They mainly include superoxide anion, hydrogen peroxide …
Pharmaceutical strategies for preventing toxicity and promoting antioxidant and anti-inflammatory actions of bilirubin
Bilirubin (BR) is the final product of haem catabolism. Disruptions along BR
metabolic/transport pathways resulting from inherited disorders can increase plasma BR …
metabolic/transport pathways resulting from inherited disorders can increase plasma BR …
[PDF][PDF] Bilirubin and atherosclerotic diseases
L Vitek - Physiological research, 2017 - biomed.cas.cz
Bilirubin is the final product of heme catabolism in the systemic circulation. For decades,
increased serum/plasma bilirubin levels were considered an ominous sign of an underlying …
increased serum/plasma bilirubin levels were considered an ominous sign of an underlying …
Genetic alterations and molecular mechanisms underlying hereditary intrahepatic cholestasis
S **e, S Wei, X Ma, R Wang, T He, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Hereditary cholestatic liver disease caused by a class of autosomal gene mutations results
in jaundice, which involves the abnormality of the synthesis, secretion, and other disorders …
in jaundice, which involves the abnormality of the synthesis, secretion, and other disorders …