Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate
Liposomes, vesicles composed of a phospholipid bilayer, are considered a remarkably
advanced drug delivery system due to their unique properties, including their …
advanced drug delivery system due to their unique properties, including their …
Biopolymer nanoparticles for nose-to-brain drug delivery: A new promising approach for the treatment of neurological diseases
Diseases affecting the central nervous system (CNS) are among the most disabling and the
most difficult to cure due to the presence of the blood–brain barrier (BBB) which represents …
most difficult to cure due to the presence of the blood–brain barrier (BBB) which represents …
Brain targeted delivery of carmustine using chitosan coated nanoparticles via nasal route for glioblastoma treatment
This study aims to develop chitosan-coated PLGA nanoparticles intended for nose-to-brain
delivery of carmustine. Formulations were prepared by the double emulsion solvent …
delivery of carmustine. Formulations were prepared by the double emulsion solvent …
Nose to brain delivery of donepezil through surface modified NLCs: Formulation development, optimization, and brain targeting study
M Yasir, A Zafar, KM Noorulla, AJ Tura… - Journal of Drug Delivery …, 2022 - Elsevier
The research was aimed to formulate the Donepezil (DPZ)-loaded nanostructured lipid
carriers (NLCs) and coated with chitosan (CH) for brain targeting through the intranasal …
carriers (NLCs) and coated with chitosan (CH) for brain targeting through the intranasal …
Self-assembling drug formulations with tunable permeability and biodegradability
G Gaynanova, L Vasileva, R Kashapov, D Kuznetsova… - Molecules, 2021 - mdpi.com
This review focuses on key topics in the field of drug delivery related to the design of
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …
Lipid-based nanocarriers via nose-to-brain pathway for central nervous system disorders
Neurodegenerative disorders are distinguished by the gradual deterioration of the nervous
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …
Lipid-based nanoparticles via nose-to-brain delivery: A mini review
Y **nchen, T **g, G Jiaoqiong - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Central nervous system disorders significantly affect the lives and health of millions of
people worldwide. Despite many therapeutic drugs are available that could potentially target …
people worldwide. Despite many therapeutic drugs are available that could potentially target …
Thymoquinone-enriched naringenin-loaded nanostructured lipid carrier for brain delivery via nasal route: in vitro prospect and in vivo therapeutic efficacy for the …
In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured
lipid carrier (NLC) was developed and delivered via the nasal route for depression …
lipid carrier (NLC) was developed and delivered via the nasal route for depression …
Formulation and optimization of naringin loaded nanostructured lipid carriers using Box-Behnken based design: In vitro and ex vivo evaluation
Naringin (NAR) is a highly abundant flavonoid found in plants. Grapefruit, citrus fruit,
oregano, and tomatoes all seem to be NAR-rich foods [1]. Numerous studies have …
oregano, and tomatoes all seem to be NAR-rich foods [1]. Numerous studies have …
The recent advancement in the chitosan-based thermosensitive hydrogel for tissue regeneration
To date, hydrogel-based scaffolds have opened new prospects for potential applications for
drug delivery and regeneration. The novel delivery strategies such as thermo-sensitive …
drug delivery and regeneration. The novel delivery strategies such as thermo-sensitive …