Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate

B Sheikholeslami, NW Lam, K Dua, M Haghi - Life Sciences, 2022 - Elsevier
Liposomes, vesicles composed of a phospholipid bilayer, are considered a remarkably
advanced drug delivery system due to their unique properties, including their …

Biopolymer nanoparticles for nose-to-brain drug delivery: A new promising approach for the treatment of neurological diseases

N Montegiove, E Calzoni, C Emiliani… - Journal of Functional …, 2022 - mdpi.com
Diseases affecting the central nervous system (CNS) are among the most disabling and the
most difficult to cure due to the presence of the blood–brain barrier (BBB) which represents …

Brain targeted delivery of carmustine using chitosan coated nanoparticles via nasal route for glioblastoma treatment

S Ahmad, I Khan, J Pandit, NA Emad, S Bano… - International Journal of …, 2022 - Elsevier
This study aims to develop chitosan-coated PLGA nanoparticles intended for nose-to-brain
delivery of carmustine. Formulations were prepared by the double emulsion solvent …

Nose to brain delivery of donepezil through surface modified NLCs: Formulation development, optimization, and brain targeting study

M Yasir, A Zafar, KM Noorulla, AJ Tura… - Journal of Drug Delivery …, 2022 - Elsevier
The research was aimed to formulate the Donepezil (DPZ)-loaded nanostructured lipid
carriers (NLCs) and coated with chitosan (CH) for brain targeting through the intranasal …

Self-assembling drug formulations with tunable permeability and biodegradability

G Gaynanova, L Vasileva, R Kashapov, D Kuznetsova… - Molecules, 2021 - mdpi.com
This review focuses on key topics in the field of drug delivery related to the design of
nanocarriers answering the biomedicine criteria, including biocompatibility, biodegradability …

Lipid-based nanocarriers via nose-to-brain pathway for central nervous system disorders

TT Nguyen, TTD Nguyen, NMA Tran, G Van Vo - Neurochemical research, 2022 - Springer
Neurodegenerative disorders are distinguished by the gradual deterioration of the nervous
system's structure and function due to oxidative stress, mitochondrial dysfunction, protein …

Lipid-based nanoparticles via nose-to-brain delivery: A mini review

Y **nchen, T **g, G Jiaoqiong - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Central nervous system disorders significantly affect the lives and health of millions of
people worldwide. Despite many therapeutic drugs are available that could potentially target …

Thymoquinone-enriched naringenin-loaded nanostructured lipid carrier for brain delivery via nasal route: in vitro prospect and in vivo therapeutic efficacy for the …

FF Qizilbash, MU Ashhar, A Zafar, Z Qamar, Annu, J Ali… - Pharmaceutics, 2022 - mdpi.com
In the current research, a thymoquinone-enriched naringenin (NGN)-loaded nanostructured
lipid carrier (NLC) was developed and delivered via the nasal route for depression …

Formulation and optimization of naringin loaded nanostructured lipid carriers using Box-Behnken based design: In vitro and ex vivo evaluation

A Alhalmi, S Amin, S Beg, R Al-Salahi, SR Mir… - Journal of Drug Delivery …, 2022 - Elsevier
Naringin (NAR) is a highly abundant flavonoid found in plants. Grapefruit, citrus fruit,
oregano, and tomatoes all seem to be NAR-rich foods [1]. Numerous studies have …

The recent advancement in the chitosan-based thermosensitive hydrogel for tissue regeneration

A Abdollahi, A Malek-Khatabi, MS Razavi… - Journal of Drug Delivery …, 2023 - Elsevier
To date, hydrogel-based scaffolds have opened new prospects for potential applications for
drug delivery and regeneration. The novel delivery strategies such as thermo-sensitive …