Eye movements in patients with neurodegenerative disorders
TJ Anderson, MR MacAskill - Nature Reviews Neurology, 2013 - nature.com
The neural pathways and brain regions involved in eye movements during ocular fixation
and gaze control include the cerebrum, brainstem and cerebellum, and abnormal eye …
and gaze control include the cerebrum, brainstem and cerebellum, and abnormal eye …
Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7
The spinocerebellar ataxias type 1 (SCA1), 2 (SCA2), 3 (SCA3), 6 (SCA6) and 7 (SCA7) are
genetically defined autosomal dominantly inherited progressive cerebellar ataxias (ADCAs) …
genetically defined autosomal dominantly inherited progressive cerebellar ataxias (ADCAs) …
Cerebellum and ocular motor control
An intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum
fine-tunes each of the subtypes of eye movements so they work together to bring and …
fine-tunes each of the subtypes of eye movements so they work together to bring and …
Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data
Summary Background Spinocerebellar ataxias (SCAs) are autosomal, dominantly inherited,
fully penetrant neurodegenerative diseases. Our aim was to study the preclinical stage of the …
fully penetrant neurodegenerative diseases. Our aim was to study the preclinical stage of the …
The preclinical stage of spinocerebellar ataxias
The autosomal dominant spinocerebellar ataxias (SCAs) are a heterogeneous group of
degenerative diseases of the cerebellum and connected regions. The discovery of various …
degenerative diseases of the cerebellum and connected regions. The discovery of various …
Spinocerebellar ataxia type 2: clinicogenetic aspects, mechanistic insights, and management approaches
Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia that
occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive …
occurs as a consequence of abnormal CAG expansions in the ATXN2 gene. Progressive …
Alterations of eye movement control in neurodegenerative movement disorders
M Gorges, EH Pinkhardt… - Journal of ophthalmology, 2014 - Wiley Online Library
The evolution of the fovea centralis, the most central part of the retina and the area of the
highest visual accuracy, requires humans to shift their gaze rapidly (saccades) to bring some …
highest visual accuracy, requires humans to shift their gaze rapidly (saccades) to bring some …
Spinocerebellar ataxia type 2: clinical presentation, molecular mechanisms, and therapeutic perspectives
Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant genetic disease
characterized by cerebellar dysfunction associated with slow saccades, early hyporeflexia …
characterized by cerebellar dysfunction associated with slow saccades, early hyporeflexia …
A comprehensive review of spinocerebellar ataxia type 2 in Cuba
Abstract Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominant cerebellar ataxia
characterized by a progressive cerebellar syndrome associated to saccadic slowing …
characterized by a progressive cerebellar syndrome associated to saccadic slowing …
Progression of early features of spinocerebellar ataxia type 2 in individuals at risk: a longitudinal study
Background The effects of ATXN2 expansion on the nervous system arise before the
cerebellar syndrome can be diagnosed; however, progression of the underlying early …
cerebellar syndrome can be diagnosed; however, progression of the underlying early …