Targeting cancer with mRNA–lipid nanoparticles: key considerations and future prospects
E Kon, N Ad-El, I Hazan-Halevy… - Nature reviews clinical …, 2023 - nature.com
Harnessing mRNA–lipid nanoparticles (LNPs) to treat patients with cancer has been an
ongoing research area that started before these versatile nanoparticles were successfully …
ongoing research area that started before these versatile nanoparticles were successfully …
Clinical translation of nanomedicines: Challenges, opportunities, and keys
Despite the massive interest and recent developments in the field of nanomedicine, only a
limited number of formulations have found their way to the clinics. This shortcoming reveals …
limited number of formulations have found their way to the clinics. This shortcoming reveals …
Microbial nano-factories: synthesis and biomedical applications
In the recent times, nanomaterials have emerged in the field of biology, medicine,
electronics, and agriculture due to their immense applications. Owing to their nanoscale …
electronics, and agriculture due to their immense applications. Owing to their nanoscale …
[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …
has recently shown promising results. However, although these advances have been …
Nanoparticle-mediated cancer cell therapy: Basic science to clinical applications
Every sixth person in the world dies due to cancer, making it the second leading severe
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …
cause of death after cardiovascular diseases. According to WHO, cancer claimed nearly 10 …
Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery
Conventional chemotherapy, one of the most widely used cancer treatment methods, has
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
serious side effects, and usually results in cancer treatment failure. Drug resistance is one of …
Ultrasound‐mediated nano‐sized drug delivery systems for cancer treatment: Multi‐scale and multi‐physics computational modeling
Computational modeling enables researchers to study and understand various complex
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …
biological phenomena in anticancer drug delivery systems (DDSs), especially nano‐sized …
An overview of polymeric nanomicelles in clinical trials and on the market
X Zheng, J **e, X Zhang, W Sun, H Zhao, Y Li… - Chinese Chemical …, 2021 - Elsevier
Polymeric nanomedicine is a promising and rapidly evolving field. Among the different
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …
Nexus between in silico and in vivo models to enhance clinical translation of nanomedicine
In cancer, one of the main barriers to effective chemotherapy is inefficient drug delivery. The
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
delivery of drugs to solid tumors involves various biochemical, biophysical, and mechanical …
Review of photoresponsive plasmonic nanoparticles that produce reactive chemical species for photodynamic therapy of cancer and bacterial infections
Increased use of classical drug therapy, including the administration of antibiotics and
anticancer drugs, has led to multidrug resistance. Overcoming this resistance requires …
anticancer drugs, has led to multidrug resistance. Overcoming this resistance requires …