Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

J Guo, X Huang, L Dou, M Yan, T Shen… - Signal Transduction and …, 2022‏ - nature.com
Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Cross-sectional and longitudinal associations between adherence to Mediterranean diet with physical performance and cognitive function in older adults: A systematic …

HJ Coelho-Júnior, A Trichopoulou, F Panza - Ageing research reviews, 2021‏ - Elsevier
Objectives The present study investigated the association between adherence to
Mediterranean diet (MeDi) and physical performance and cognitive function in older adults …

[HTML][HTML] Microbiota-immune-brain interactions: A lifespan perspective

A Ratsika, JSC Pereira, CMK Lynch, G Clarke… - Current Opinion in …, 2023‏ - Elsevier
There is growing appreciation of key roles of the gut microbiota in maintaining homeostasis
and influencing brain and behaviour at critical windows across the lifespan. Mounting …

Influence of the Mediterranean diet on healthy aging

MC Andreo-López, V Contreras-Bolívar… - International Journal of …, 2023‏ - mdpi.com
The life expectancy of the global population has increased. Aging is a natural physiological
process that poses major challenges in an increasingly long-lived and frail population …

Dietary patterns and Alzheimer's disease: an updated review linking nutrition to neuroscience

I Ellouze, J Sheffler, R Nagpal, B Arjmandi - Nutrients, 2023‏ - mdpi.com
Alzheimer's disease (AD) is a growing concern for the aging population worldwide. With no
current cure or reliable treatments available for AD, prevention is an important and growing …

Mediterranean diet and cognitive function: From methodology to mechanisms of action

M Siervo, OM Shannon, DJ Llewellyn… - Free Radical Biology …, 2021‏ - Elsevier
Abstract The traditional Mediterranean diet (MedDiet), rich in minimally processed plant
foods and fish, has been widely recognized to be one of the healthiest diets. Data from …

Attenuation of 7-ketocholesterol-and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age …

T Nury, A Yammine, I Ghzaiel, K Sassi, A Zarrouk… - Ageing research …, 2021‏ - Elsevier
Age-related diseases for which there are no effective treatments include cardiovascular
diseases; neurodegenerative diseases such as Alzheimer's disease; eye disorders such as …

Essential nutrients, added sugar intake, and epigenetic age in midlife Black and White women: NIMHD Social Epigenomics Program

DT Chiu, EJ Hamlat, J Zhang, ES Epel… - JAMA Network …, 2024‏ - jamanetwork.com
Importance Nutritive compounds play critical roles in DNA replication, maintenance, and
repair, and also serve as antioxidant and anti-inflammatory agents. Sufficient dietary intakes …

Memorable food: fighting age-related neurodegeneration by precision nutrition

M Milošević, A Arsić, Z Cvetković, V Vučić - Frontiers in Nutrition, 2021‏ - frontiersin.org
Healthcare systems worldwide are seriously challenged by a rising prevalence of
neurodegenerative diseases (NDDs), which mostly, but not exclusively, affect the ever …

Hallmarks of ageing in human skeletal muscle and implications for understanding the pathophysiology of sarcopenia in women and men

A Granic, K Suetterlin, T Shavlakadze… - Clinical …, 2023‏ - portlandpress.com
Ageing is a complex biological process associated with increased morbidity and mortality.
Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and …