The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of
endothelial cells. It has been linked to the physiological functioning of the microcirculation …

The endothelium is lined by a protective mesh of proteins and carbohydrates called the
endothelial glycocalyx (EG). This layer creates a negatively charged gel-like barrier between …

Even with extensive transfusion support, trauma-induced bleeding often leads to death.
Early intervention may improve outcomes, yet which blood products, factor concentrates, or …

OBJECTIVE To describe changes in circulating hyaluronic acid (HA) concentration, a
biomarker of endothelial glycocalyx degradation, after administration of fresh-frozen plasma …

Hyperfibrinolysis (HF) frequently occurs after severe systemic hypoperfusion during major
trauma and out-of-hospital cardiac arrest (OHCA). In trauma-induced HF, hypoperfusion, the …

BACKGROUND Heparan sulfate is an integral component of the glycocalyx that provides an
anticoagulant layer close to the endothelium. Hypoperfusion, inflammation, and …

Four-factor Prothrombin Complex Concentrate Use for Bleeding Management in Adult Trauma
- PMC Skip to main content Here's how you know Official websites use .gov A .gov website …

Abdominal trauma (AT) is of major global importance, particularly because the civil,
terroristic, and military traumatic potential of blast injuries has increased. The consequences …

Background: Microvascular leakage is proposed as main contributor to disturbed
microcirculatory perfusion following hemorrhagic shock and fluid resuscitation, leading to …

Objective: To explore the effect of restricted fluid resuscitation on coagulation, the serum
inflammatory factors, and the prognoses of patients with traumatic hemorrhagic shock …