Effect of exosomal miRNA on cancer biology and clinical applications

Z Sun, K Shi, S Yang, J Liu, Q Zhou, G Wang, J Song… - Molecular cancer, 2018 - Springer
Exosomes, extracellular vesicles with diameters ranging from 30 to 150 nm, are widely
present in various body fluids. Recently, microRNAs (miRNAs) have been identified in …

[HTML][HTML] Biogenesis and function of extracellular vesicles in cancer

MP Bebelman, MJ Smit, DM Pegtel… - Pharmacology & …, 2018 - Elsevier
Extracellular vesicles (EVs) are heterogeneous multi-signal messengers that support cancer
growth and dissemination by mediating the tumor-stroma crosstalk. Exosomes are a subtype …

Extracellular signals regulate the biogenesis of extracellular vesicles

Y **, L Ma, W Zhang, W Yang, Q Feng, H Wang - Biological research, 2022 - Springer
Extracellular vesicles (EVs) are naturally released membrane vesicles that act as carriers of
proteins and RNAs for intercellular communication. With various biomolecules and specific …

Biology and biogenesis of shed microvesicles

C Tricarico, J Clancy, C D'Souza-Schorey - Small GTPases, 2017 - Taylor & Francis
The ability of cells to transmit bioactive molecules to recipient cells and the extracellular
environment is a fundamental requirement for both normal physiology and disease …

Comprehensive landscape of extracellular vesicle-derived RNAs in cancer initiation, progression, metastasis and cancer immunology

W Hu, C Liu, ZY Bi, Q Zhou, H Zhang, LL Li, J Zhang… - Molecular cancer, 2020 - Springer
Extracellular vesicles (EVs), a class of heterogeneous membrane vesicles, are generally
divided into exosomes and microvesicles on basis of their origination from the endosomal …

The origin and functions of exosomes in cancer

C Rajagopal, KB Harikumar - Frontiers in oncology, 2018 - frontiersin.org
Exosomes are nanovesicles having a maximum size of 150 nm and is a newly emerging
focus in various fields of research. Its role in cargo trafficking along with its differential …

Non-exosomal and exosomal circulatory microRNAs: which are more valid as biomarkers?

NNSB Nik Mohamed Kamal… - Frontiers in …, 2020 - frontiersin.org
MicroRNAs (miRNAs) are a group of small non-coding RNAs with approximately 19–25
nucleotides that are involved in regulating a range of developmental and physiological …

The biology of extracellular microvesicles

AE Sedgwick, C D'Souza‐Schorey - Traffic, 2018 - Wiley Online Library
The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to
recent advances in the realization of their significant contributions to normal physiology and …

Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles

VR Minciacchi, S You, C Spinelli, S Morley… - …, 2015 - pmc.ncbi.nlm.nih.gov
Large oncosomes (LO) are atypically large (1-10μm diameter) cancer-derived extracellular
vesicles (EVs), originating from the shedding of membrane blebs and associated with …

Biogenesis of extracellular vesicles

T Kang, I Atukorala, S Mathivanan - New frontiers: extracellular vesicles, 2021 - Springer
Extracellular vesicles (EVs) refer to vesicles that are released by cells into the extracellular
space. EVs mediate cell-to-cell communication via delivery of functional biomolecules …