Exploring the multifunctionality of SR proteins
I Slišković, H Eich… - Biochemical Society …, 2022 - portlandpress.com
Members of the arginine–serine-rich protein family (SR proteins) are multifunctional RNA-
binding proteins that have emerged as key determinants for mRNP formation, identity and …
binding proteins that have emerged as key determinants for mRNP formation, identity and …
Long non-coding RNAs in cardiac hypertrophy and heart failure: Functions, mechanisms and clinical prospects
The surge in reports describing non-coding RNAs (ncRNAs) has focused attention on their
possible biological roles and effects on development and disease. ncRNAs have been …
possible biological roles and effects on development and disease. ncRNAs have been …
Higher order dynamic mode decomposition: From fluid dynamics to heart disease analysis
In this work, we study in detail the performance of Higher Order Dynamic Mode
Decomposition (HODMD) technique when applied to echocardiography images. HODMD is …
Decomposition (HODMD) technique when applied to echocardiography images. HODMD is …
Cardiac splicing as a diagnostic and therapeutic target
Despite advances in therapeutics for heart failure and arrhythmias, a substantial proportion
of patients with cardiomyopathy do not respond to interventions, indicating a need to identify …
of patients with cardiomyopathy do not respond to interventions, indicating a need to identify …
Long noncoding RNAs in ubiquitination, protein degradation, and human diseases
Protein stability and turnover is critical in normal cellular and physiological process and their
misregulation may contribute to accumulation of unwanted proteins causing cellular …
misregulation may contribute to accumulation of unwanted proteins causing cellular …
[HTML][HTML] Splicing factors in the heart: Uncovering shared and unique targets
Alternative splicing generates specialized protein isoforms that allow the heart to adapt
during development and disease. The recent discovery that mutations in the splicing factor …
during development and disease. The recent discovery that mutations in the splicing factor …
Exosomal hsa-mir-335-5p and hsa-mir-483-5p are novel biomarkers for rheumatoid arthritis: a development and validation study
Y Yu, S Park, H Lee, EJ Kwon, HR Park, YH Kim… - International …, 2023 - Elsevier
Background Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes
cartilage and bone damage. Exosomes are small extracellular vesicles that play a critical …
cartilage and bone damage. Exosomes are small extracellular vesicles that play a critical …
Retard or exacerbate: role of long non-coding RNA growth arrest-specific 5 in the fibrosis
Z **ang, Y Liqing, Y Qingqing, H Qiang… - Cytokine & Growth Factor …, 2022 - Elsevier
Fibrosis is the endpoint of pathological remodeling involving different expressions of non-
coding RNA (ncRNA) including long non-coding RNA growth arrest-specific 5 (lncRNA …
coding RNA (ncRNA) including long non-coding RNA growth arrest-specific 5 (lncRNA …
Stretching muscle cells induces transcriptional and splicing transitions and changes in SR proteins
ER Hinkle, RE Blue, YH Tsai, M Combs, J Davi… - Communications …, 2022 - nature.com
Alternative splicing is an RNA processing mechanism involved in skeletal muscle
development and pathology. Muscular diseases exhibit splicing alterations and changes in …
development and pathology. Muscular diseases exhibit splicing alterations and changes in …
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1
AM Santamans, V Montalvo-Romeral, A Mora… - PLoS …, 2021 - journals.plos.org
During the first weeks of postnatal heart development, cardiomyocytes undergo a major
adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This …
adaptive metabolic shift from glycolytic energy production to fatty acid oxidation. This …