[HTML][HTML] The contribution of physical exercise to brain resilience

RM Arida, L Teixeira-Machado - Frontiers in behavioral neuroscience, 2021 - frontiersin.org
Increasing attention has been given to understanding resilience to brain diseases, often
described as brain or cognitive reserve. Among the protective factors for the development of …

An updated reappraisal of synapsins: structure, function and role in neurological and psychiatric disorders

F Longhena, G Faustini, V Brembati, M Pizzi… - Neuroscience & …, 2021 - Elsevier
Synapsins (Syns) are phosphoproteins strongly involved in neuronal development and
neurotransmitter release. Three distinct genes SYN1, SYN2 and SYN3, with elevated …

[HTML][HTML] Physical exercise and seizure activity

RM Arida - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2021 - Elsevier
Neuroprotective and antiepileptogenic therapies have been extensively investigated for
epilepsy prevention and treatment. This review gives an overview of the promising …

[HTML][HTML] Exercise-linked consequences on epilepsy

BRR Cavalcante, AC Improta-Caria, VH de Melo… - Epilepsy & Behavior, 2021 - Elsevier
Objective Epilepsy is a brain disorder that leads to seizures and neurobiological, cognitive,
psychological, and social consequences. Physical inactivity can contribute to worse epilepsy …

[HTML][HTML] Update on first unprovoked seizure in children and adults: A narrative review

MJ Jiménez-Villegas, L Lozano-García… - Seizure, 2021 - Elsevier
Objective First seizures are always challenging for physicians. Determining etiology, risk of
recurrence, need for diagnostic electroencephalogram (EEG) or neuroimaging, balancing …

Effects of an exercise program on health of people with epilepsy: A randomized clinical trial

CA Häfele, AJ Rombaldi, N Feter, V Häfele… - Epilepsy & Behavior, 2021 - Elsevier
To evaluate the effects of an exercise program on the health of people with epilepsy (PWE)
and seizure frequency. A randomized clinical trial was carried out in Pelotas/Brazil …

Drivers for the comorbidity of type 2 diabetes mellitus and epilepsy: a sco** review

NA Shlobin, JW Sander - Epilepsy & Behavior, 2020 - Elsevier
Epilepsy, a common neurologic condition, is associated with a greater prevalence of type 2
diabetes mellitus (T2DM). We examined potential drivers for the comorbidity of epilepsy and …

Voluntary running wheel activity reduces seizure burden and affords neuroprotection in a mouse model of acquired epilepsy

V Kebede, R Di Sapia, N Tonesi, M Rizzi, S Balosso… - …, 2025 - Wiley Online Library
Objective Physical exercise may improve neurological deficits and neuronal damage after
acute brain injuries and decrease established seizures. We investigated whether voluntary …

The potential role of previous physical exercise program to reduce seizure susceptibility: a systematic review and meta-analysis of animal studies

RM Arida, AA Passos, AL Graciani, JAF Brogin… - Frontiers in …, 2021 - frontiersin.org
Background: Clinical and pre-clinical studies indicate a reduction in seizure frequency as
well as a decrease in susceptibility to subsequently evoked seizures after physical exercise …

[HTML][HTML] Reduced epilepsy development in synapsin 2 knockout mice with autistic behavior following early systemic treatment with interleukin-6 receptor antibody

F Bäckström, M Ahl, J Wickham, CT Ekdahl - Epilepsy Research, 2023 - Elsevier
Background Individuals with autism spectrum disorder (ASD) have an increased risk of
develo** epilepsy. Both ASD and epilepsy have been associated with increased levels of …