A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen-and oxygen-containing heterocyclic scaffolds

TM Dhameliya, HA Donga, PV Vaghela, BG Panchal… - RSC …, 2020 - pubs.rsc.org
Heterocycles have been found to be of much importance as several nitrogen-and oxygen-
containing heterocycle compounds exist amongst the various USFDA-approved drugs …

External oxidant-free oxidative cross-coupling: a photoredox cobalt-catalyzed aromatic C–H thiolation for constructing C–S bonds

G Zhang, C Liu, H Yi, Q Meng, C Bian… - Journal of the …, 2015 - ACS Publications
An external oxidant-free oxidative coupling for aromatic C–H thiolation by visible-light
photoredox cobalt-catalysis has been developed. Various substrates could afford …

A reusable Co catalyst for the selective hydrogenation of functionalized nitroarenes and the direct synthesis of imines and benzimidazoles from nitroarenes and …

T Schwob, R Kempe - Angewandte Chemie International …, 2016 - Wiley Online Library
The use of abundantly available transition metals in reactions that have been preferentially
mediated by rare noble metals, for example, hydrogenations, is a desirable aim in catalysis …

Tunable Triazole‐Phosphine‐Copper Catalysts for the Synthesis of 2‐Aryl‐1H‐benzo[d]imidazoles from Benzyl Alcohols and Diamines by Acceptorless …

Z Xu, DS Wang, X Yu, Y Yang… - Advanced Synthesis & …, 2017 - Wiley Online Library
Triazole‐phosphine‐copper complexes (TAP− Cu) have been synthesized and applied as
tunable and efficient catalysts for the selective synthesis of fluoro‐substituted 2‐aryl‐1H …

The synthesis of benzimidazoles and quinoxalines from aromatic diamines and alcohols by iridium‐catalyzed acceptorless dehydrogenative alkylation

T Hille, T Irrgang, R Kempe - Chemistry–A European Journal, 2014 - Wiley Online Library
Benzimidazoles and quinoxalines are important N‐heteroaromatics with many applications
in pharmaceutical and chemical industry. Here, the synthesis of both classes of compounds …

Developments towards regioselective synthesis of 1, 2‐disubstituted benzimidazoles

LCR Carvalho, E Fernandes… - Chemistry–A European …, 2011 - Wiley Online Library
Disubstituted benzimidazoles play an important role in several areas and particularly as
drug discovery targets. Herein, several methods to assemble these structures are reviewed …

Cobalt-Catalyzed Sustainable Synthesis of Benzimidazoles by Redox-Economical Coupling of o-Nitroanilines and Alcohols

S Das, S Mallick, S De Sarkar - The Journal of Organic Chemistry, 2019 - ACS Publications
This study reveals cobalt-catalyzed sustainable synthesis of benzimidazoles by redox-
economical coupling of o-nitroanilines and alcohols. The major advantage of this report is …

Cu-catalyzed three-component synthesis of substituted benzothiazoles in water.

H Deng, Z Li, F Ke, X Zhou - Chemistry (Weinheim an der …, 2012 - europepmc.org
Three in one: Copper-catalyzed three-component reactions, involving 2-iodoanilines,
aldehydes, and sulfur powder, afford 2-phenylbenzothiazoles in water. A variety of 2 …

A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice

A Illendula, JA Pulikkan, H Zong, J Grembecka, L Xue… - Science, 2015 - science.org
Acute myeloid leukemia (AML) is the most common form of adult leukemia. The transcription
factor fusion CBFβ-SMMHC (core binding factor β and the smooth-muscle myosin heavy …