Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation
M Chehelgerdi, M Chehelgerdi, OQB Allela… - Molecular cancer, 2023 - Springer
The use of nanotechnology has the potential to revolutionize the detection and treatment of
cancer. Developments in protein engineering and materials science have led to the …
cancer. Developments in protein engineering and materials science have led to the …
Engineered nanoparticles for drug delivery in cancer therapy
In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …
number of issues associated with conventional therapeutic agents, including their poor …
Inhibition of glycolysis-driven immunosuppression with a nano-assembly enhances response to immune checkpoint blockade therapy in triple negative breast cancer
X Ren, Z Cheng, J He, X Yao, Y Liu, K Cai, M Li… - Nature …, 2023 - nature.com
Immune-checkpoint inhibitors (ICI) are promising modalities for treating triple negative
breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor …
breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor …
Aptamer-based targeted delivery of functional nucleic acids
S ** chemistries that facilitate nanotechnology
KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …
Aptamer-functionalized nanoparticles in targeted delivery and cancer therapy
Z Fu, J **ang - International Journal of Molecular Sciences, 2020 - mdpi.com
Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …
RNA interference-based therapy and its delivery systems
X Chen, LS Mangala, C Rodriguez-Aguayo… - Cancer and Metastasis …, 2018 - Springer
RNA interference (RNAi) is considered a highly specific approach for gene silencing and
holds tremendous potential for treatment of various pathologic conditions such as …
holds tremendous potential for treatment of various pathologic conditions such as …
Oligonucleotide aptamers: new tools for targeted cancer therapy
H Sun, X Zhu, PY Lu, RR Rosato, W Tan… - Molecular Therapy-Nucleic …, 2014 - cell.com
Aptamers are a class of small nucleic acid ligands that are composed of RNA or single-
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …
stranded DNA oligonucleotides and have high specificity and affinity for their targets. Similar …